Bryce A. Harrison, Ph.D.

Affiliations: 
2003 Harvard University, Cambridge, MA, United States 
Area:
control of gene expression and preservation of genomic integrity
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"Bryce Harrison"
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Gregory L. Verdine grad student 2003 Harvard
 (The synthesis and biologic evaluation of exhaustively stereodiversified libraries of acyclic 1,5-enediols.)
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Bursavich MG, Harrison BA, Acharya R, et al. (2017) Design, Synthesis and Evaluation of a Novel Series of Oxadiazine Gamma Secretase Modulators for Familial Alzheimer's Disease. Journal of Medicinal Chemistry
Shi Z, Harrison BA, Verdine GL. (2003) Unpredictable stereochemical preferences for mu opioid receptor activity in an exhaustively stereodiversified library of 1,4-enediols. Organic Letters. 5: 633-6
Harrison BA, Pasternak GW, Verdine GL. (2003) 2,6-Dimethyltyrosine analogues of a stereodiversified ligand library: highly potent, selective, non-peptidic mu opioid receptor agonists. Journal of Medicinal Chemistry. 46: 677-80
Harrison BA, Gierasch TM, Neilan C, et al. (2002) High-affinity mu opioid receptor ligands discovered by the screening of an exhaustively stereodiversified library of 1,5-enediols. Journal of the American Chemical Society. 124: 13352-3
Harrison BA, Verdine GL. (2001) The synthesis of an exhaustively stereodiversified library of cis-1,5 enediols by silyl-tethered ring-closing metathesis. Organic Letters. 3: 2157-9
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