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Juan J. Fung, Ph.D.

Affiliations: 
2009 Stanford University, Palo Alto, CA 
Area:
Adrenergic receptors
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"Juan Fung"
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Parents

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Brian K. Kobilka grad student 2009 Stanford
 (Structural dynamics of G protein-coupled receptor monomers and oligomers: Insights from the beta2-adrenergic receptor.)

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Publications

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Walsh SM, Mathiasen S, Christensen SM, et al. (2018) Single Proteoliposome High-Content Analysis Reveals Differences in the Homo-Oligomerization of GPCRs. Biophysical Journal. 115: 300-312
DeVree BT, Mahoney JP, Vélez-Ruiz GA, et al. (2016) Allosteric coupling from G protein to the agonist-binding pocket in GPCRs. Nature
Mathiasen S, Christensen SM, Fung JJ, et al. (2014) Nanoscale high-content analysis using compositional heterogeneities of single proteoliposomes. Nature Methods. 11: 931-4
Nygaard R, Zou Y, Dror RO, et al. (2013) The dynamic process of β(2)-adrenergic receptor activation. Cell. 152: 532-42
Zhang C, Srinivasan Y, Arlow DH, et al. (2012) High-resolution crystal structure of human protease-activated receptor 1. Nature. 492: 387-92
Zocher M, Fung JJ, Kobilka BK, et al. (2012) Ligand-specific interactions modulate kinetic, energetic, and mechanical properties of the human β2 adrenergic receptor. Structure (London, England : 1993). 20: 1391-402
Rasmussen SG, Choi HJ, Fung JJ, et al. (2011) Structure of a nanobody-stabilized active state of the β(2) adrenoceptor. Nature. 469: 175-80
Bokoch MP, Zou Y, Rasmussen SG, et al. (2010) Ligand-specific regulation of the extracellular surface of a G-protein-coupled receptor. Nature. 463: 108-12
Fung JJ, Deupi X, Pardo L, et al. (2009) Ligand-regulated oligomerization of beta(2)-adrenoceptors in a model lipid bilayer. The Embo Journal. 28: 3315-28
Granier S, Kim S, Fung JJ, et al. (2009) FRET-based measurement of GPCR conformational changes. Methods in Molecular Biology (Clifton, N.J.). 552: 253-68
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