Jermont Chen, Ph.D.
Affiliations: | 2008 | Princeton University, Princeton, NJ |
Area:
Synthetic Biology and Alzheimer's DiseaseGoogle:
"Jermont Chen"Mean distance: 9.31 | S | N | B | C | P |
Parents
Sign in to add mentor| Michael H. Hecht | grad student | 2008 | Princeton | |
| (Using high throughput screens to identify lead compounds for Alzheimer's disease therapeutics.) | ||||
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Publications
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| McKoy AF, Chen J, Schupbach T, et al. (2014) Structure-activity relationships for a series of compounds that inhibit aggregation of the Alzheimer's peptide, Aβ42. Chemical Biology & Drug Design. 84: 505-12 |
| McKoy AF, Chen J, Schupbach T, et al. (2012) A novel inhibitor of amyloid β (Aβ) peptide aggregation: from high throughput screening to efficacy in an animal model of Alzheimer disease. The Journal of Biological Chemistry. 287: 38992-9000 |
| Armstrong AH, Chen J, McKoy AF, et al. (2011) Mutations that replace aromatic side chains promote aggregation of the Alzheimer's Aβ peptide. Biochemistry. 50: 4058-67 |
| Chen J, Armstrong AH, Koehler AN, et al. (2010) Small molecule microarrays enable the discovery of compounds that bind the Alzheimer's Aβ peptide and reduce its cytotoxicity. Journal of the American Chemical Society. 132: 17015-22 |