Colleen T. O'Loughlin, Ph.D.

Affiliations: 
2014 Molecular Biology Princeton University, Princeton, NJ 
Area:
molecular mechanisms that bacteria use for intercellular communication
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"Colleen O'Loughlin"
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Parents

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Bonnie L. Bassler grad student 2014 Princeton
 (Manipulating quorum sensing to control bacterial pathogenicity.)
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Publications

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Tran A, Tang A, O'Loughlin CT, et al. (2017) C. elegans avoids toxin-producing Streptomyces using a seven transmembrane domain chemosensory receptor. Elife. 6
Miller LC, O'Loughlin CT, Zhang Z, et al. (2015) Development of potent inhibitors of pyocyanin production in Pseudomonas aeruginosa. Journal of Medicinal Chemistry. 58: 1298-306
O'Loughlin CT, Miller LC, Siryaporn A, et al. (2013) A quorum-sensing inhibitor blocks Pseudomonas aeruginosa virulence and biofilm formation. Proceedings of the National Academy of Sciences of the United States of America. 110: 17981-6
Chen G, Swem LR, Swem DL, et al. (2011) A strategy for antagonizing quorum sensing. Molecular Cell. 42: 199-209
Swem LR, Swem DL, O'Loughlin CT, et al. (2009) A quorum-sensing antagonist targets both membrane-bound and cytoplasmic receptors and controls bacterial pathogenicity. Molecular Cell. 35: 143-53
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