Maria M. Bednar, Ph.D.

Affiliations: 
2011 Chemistry Duke University, Durham, NC 
Area:
chemical biology, mechanistic enzymology and molecular medicine
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Dewey G. McCafferty grad student 2011 Duke
 (Insights into Chlamydial Protease-Like Activity Factor (CPAF).)
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Publications

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Dudiak BM, Maksimchuk KR, Bednar MM, et al. (2019) Insights into the Autoproteolytic Processing and Catalytic Mechanism of the Virulence-Associated Protease CPAF. Biochemistry
Hoertz AJ, Hamburger JB, Gooden DM, et al. (2012) Studies on the biosynthesis of the lipodepsipeptide antibiotic Ramoplanin A2. Bioorganic & Medicinal Chemistry. 20: 859-65
Bednar MM, Jorgensen I, Valdivia RH, et al. (2011) Chlamydia protease-like activity factor (CPAF): characterization of proteolysis activity in vitro and development of a nanomolar affinity CPAF zymogen-derived inhibitor. Biochemistry. 50: 7441-3
Jorgensen I, Bednar MM, Amin V, et al. (2011) The Chlamydia protease CPAF regulates host and bacterial proteins to maintain pathogen vacuole integrity and promote virulence. Cell Host & Microbe. 10: 21-32
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