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Jacob Stewart-Ornstein, Ph.D.

Affiliations: 
2012 Biochemistry and Molecular Biology University of California, San Francisco, San Francisco, CA 
Area:
Proteomics, Protein Folding, and Prion-Based Inheritance in Disease and Normal Biology
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"Jacob Stewart-Ornstein"
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Jonathan S. Weissman grad student 2012 UCSF
 (Dimensionality and the Stress/Growth Axis of Gene Expression in S. cerevisiae.)

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Publications

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Chen SY, Osimiri LC, Chevalier M, et al. (2020) Optogenetic Control Reveals Differential Promoter Interpretation of Transcription Factor Nuclear Translocation Dynamics. Cell Systems
Hafner A, Reyes J, Stewart-Ornstein J, et al. (2020) Quantifying the Central Dogma in the p53 Pathway in Live Single Cells. Cell Systems
Reyes J, Chen JY, Stewart-Ornstein J, et al. (2018) Fluctuations in p53 Signaling Allow Escape from Cell-Cycle Arrest. Molecular Cell
Endress JE, Harris IS, Stewart-Ornstein J, et al. (2018) Abstract 1851: Combined inhibition of PARP and the unfolded protein response synergistically reduces viability in BRCA1-mutant breast cancer cells Cancer Research. 78: 1851-1851
Stewart-Ornstein J, Cheng HWJ, Lahav G. (2017) Conservation and Divergence of p53 Oscillation Dynamics across Species. Cell Systems
Stewart-Ornstein J, Lahav G. (2017) Integrating genomic information and signaling dynamics for efficient cancer therapy. Current Opinion in Systems Biology. 1: 38-43
Hafner A, Stewart-Ornstein J, Purvis JE, et al. (2017) p53 pulses lead to distinct patterns of gene expression albeit similar DNA-binding dynamics. Nature Structural & Molecular Biology
Stewart-Ornstein J, Lahav G. (2017) p53 dynamics in response to DNA damage vary across cell lines and are shaped by efficiency of DNA repair and activity of the kinase ATM. Science Signaling. 10
Stewart-Ornstein J, Chen S, Bhatnagar R, et al. (2017) Model-guided optogenetic study of PKA signaling in budding yeast. Molecular Biology of the Cell. 28: 221-227
Stewart-Ornstein J, Lahav G. (2016) Dynamics of CDKN1A in Single Cells Defined by an Endogenous Fluorescent Tagging Toolkit. Cell Reports
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