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Matthew D. Hassink, Ph.D.

Affiliations: 
2012 Chemistry and Biochemistry University of Delaware, Newark, DE, United States 
Area:
Organic chemistry
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Joseph M. Fox grad student 2012 University of Delaware
 (Methods for carbon-carbon bond construction and in vivo imaging based on strained molecules.)
Daniel H. Appella post-doc 2014 National Institutes of Health

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Publications

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Yang Y, Zhu J, Hassink M, et al. (2017) A novel preventive strategy against HIV-1 infection: combinatorial use of inhibitors targeting the nucleocapsid and fusion proteins. Emerging Microbes & Infections. 6: e40
Hartman TL, Yang L, Helfrick AN, et al. (2016) Preclinical evaluation of a mercaptobenzamide and its prodrug for NCp7-Targeted inhibition of human immunodeficiency virus. Antiviral Research
Liu S, Hassink M, Selvaraj R, et al. (2013) Efficient 18F labeling of cysteine-containing peptides and proteins using tetrazine-trans-cyclooctene ligation. Molecular Imaging. 12: 121-8
Wu Z, Liu S, Hassink M, et al. (2013) Development and evaluation of 18F-TTCO-Cys40-Exendin-4: a PET probe for imaging transplanted islets. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. 54: 244-51
Hassink MD, Fox JM. (2012) Functionalized Cyclopropenes and Methylenecyclopropenes from Dianions of 3-Hydroxymethylcyclopropenes. Synthesis. 44: 2843-2850
Selvaraj R, Liu S, Hassink M, et al. (2011) Tetrazine-trans-cyclooctene ligation for the rapid construction of integrin αvβ₃ targeted PET tracer based on a cyclic RGD peptide. Bioorganic & Medicinal Chemistry Letters. 21: 5011-4
Hassink M, Liu X, Fox JM. (2011) Copper-catalyzed synthesis of 2,4-disubstituted allenoates from α-diazoesters. Organic Letters. 13: 2388-91
Li Z, Cai H, Hassink M, et al. (2010) Tetrazine-trans-cyclooctene ligation for the rapid construction of 18F labeled probes. Chemical Communications (Cambridge, England). 46: 8043-5
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