Melisa M. Cherney, Ph.D.

Affiliations: 
2007 University of Wisconsin, Madison, Madison, WI 
Area:
Bioinorganic Chemistry, Allostery in Gas Sensing Metalloproteins, Metallosensor design
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"Melisa Cherney"
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Judith N. Burstyn grad student 2007 UW Madison
 (Studies of the heme proteins soluble guanylyl cyclase and cystathionine beta -synthase.)
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Publications

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Frederick AK, Thompson SL, Vakharia ZM, et al. (2022) Effect on intrinsic peroxidase activity of substituting coevolved residues from Ω-loop C of human cytochrome c into yeast iso-1-cytochrome c. Journal of Inorganic Biochemistry. 232: 111819
McClelland LJ, Mou T, Jeakins-Cooley ME, et al. (2014) Alternative Conformations of Yeast Iso-1-Cytochrome C: Effects of a Gatekeeping Residue on Heme Crevice Dynamics Biophysical Journal. 106: 226a-227a
Cherney MM, Junior CC, Bowler BE. (2013) Mutation of trimethyllysine 72 to alanine enhances His79-heme-mediated dynamics of iso-1-cytochrome c. Biochemistry. 52: 837-46
Cherney MM, Zhang Y, James MN, et al. (2012) Structure-activity characterization of sulfide:quinone oxidoreductase variants. Journal of Structural Biology. 178: 319-28
Bateman KS, Cherney MM, Mahuran DJ, et al. (2011) Crystal structure of β-hexosaminidase B in complex with pyrimethamine, a potential pharmacological chaperone. Journal of Medicinal Chemistry. 54: 1421-9
Sankaranarayanan R, Cherney MM, Garen C, et al. (2010) The molecular structure of ornithine acetyltransferase from Mycobacterium tuberculosis bound to ornithine, a competitive inhibitor. Journal of Molecular Biology. 397: 979-90
Ostrowski AD, Deakin SJ, Azhar B, et al. (2010) Nitric oxide photogeneration from trans-Cr(cyclam)(ONO)(2)(+) in a reducing environment. activation of soluble guanylyl cyclase and arterial vasorelaxation. Journal of Medicinal Chemistry. 53: 715-22
Miller TW, Cherney MM, Lee AJ, et al. (2009) The effects of nitroxyl (HNO) on soluble guanylate cyclase activity: interactions at ferrous heme and cysteine thiols. The Journal of Biological Chemistry. 284: 21788-96
Pillai B, Moorthie VA, van Belkum MJ, et al. (2009) Crystal structure of diaminopimelate epimerase from Arabidopsis thaliana, an amino acid racemase critical for L-lysine biosynthesis. Journal of Molecular Biology. 385: 580-94
Watanabe N, Clay MD, van Belkum MJ, et al. (2008) Mechanism of substrate recognition and PLP-induced conformational changes in LL-diaminopimelate aminotransferase from Arabidopsis thaliana. Journal of Molecular Biology. 384: 1314-29
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