Yan Jia, Ph.D.
Affiliations: | 2010 | Chemistry | University of Minnesota, Twin Cities, Minneapolis, MN |
Area:
development of approaches that will deliver anticancers drug, proteins and nucleic acids to cancer tissues and not normal tissuesGoogle:
"Yan Jia"Mean distance: 9.13
Parents
Sign in to add mentor| Carston R. Wagner | grad student | 2010 | UMN | |
| (Development and delivery of eukaryotic initiation factor 4E (eIF4E) antagonists as potential anticancer therapeutics.) | ||||
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Publications
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| Li S, Jia Y, Jacobson B, et al. (2013) Treatment of breast and lung cancer cells with a N-7 benzyl guanosine monophosphate tryptamine phosphoramidate pronucleotide (4Ei-1) results in chemosensitization to gemcitabine and induced eIF4E proteasomal degradation. Molecular Pharmaceutics. 10: 523-31 |
| Jia Y, Polunovsky V, Bitterman PB, et al. (2012) Cap-dependent translation initiation factor eIF4E: an emerging anticancer drug target. Medicinal Research Reviews. 32: 786-814 |
| Jia Y, Chiu TL, Amin EA, et al. (2010) Design, synthesis and evaluation of analogs of initiation factor 4E (eIF4E) cap-binding antagonist Bn7-GMP. European Journal of Medicinal Chemistry. 45: 1304-13 |
| Ghosh B, Benyumov AO, Ghosh P, et al. (2009) Nontoxic chemical interdiction of the epithelial-to-mesenchymal transition by targeting cap-dependent translation. Acs Chemical Biology. 4: 367-77 |
| Ghosh P, Cheng J, Chou TF, et al. (2008) Expression, purification and characterization of recombinant mouse translation initiation factor eIF4E as a dihydrofolate reductase (DHFR) fusion protein. Protein Expression and Purification. 60: 132-9 |