Chaim A. Schramm, Ph.D.

Affiliations: 
2012 Biochemistry and Molecular Biophysics University of Pennsylvania, Philadelphia, PA, United States 
Area:
Organic Chemistry, Chemical Biology, De Novo Protein Design
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"Chaim Schramm"
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Parents

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William F. DeGrado grad student 2012 Penn
 (Using structural bioinformatics to understand and design protein structures and interactions.)
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Publications

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Roark RS, Li H, Williams WB, et al. (2020) Recapitulation of HIV-1 Env-antibody coevolution in macaques leading to neutralization breadth. Science (New York, N.Y.)
Wu NC, Andrews SF, Raab JE, et al. (2020) Convergent Evolution in Breadth of Two V6-1-Encoded Influenza Antibody Clonotypes from a Single Donor. Cell Host & Microbe
Rantalainen K, Berndsen ZT, Antanasijevic A, et al. (2020) HIV-1 Envelope and MPER Antibody Structures in Lipid Assemblies. Cell Reports. 31: 107583
Olson BJ, Moghimi P, Schramm CA, et al. (2019) sumrep: A Summary Statistic Framework for Immune Receptor Repertoire Comparison and Model Validation. Frontiers in Immunology. 10: 2533
Gorman J, Mason RD, Nettey L, et al. (2019) Isolation and Structure of an Antibody that Fully Neutralizes Isolate SIVmac239 Reveals Functional Similarity of SIV and HIV Glycan Shields. Immunity
Ohlin M, Scheepers C, Corcoran M, et al. (2019) Inferred Allelic Variants of Immunoglobulin Receptor Genes: A System for Their Evaluation, Documentation, and Naming. Frontiers in Immunology. 10: 435
Krebs SJ, Kwon YD, Schramm CA, et al. (2019) Longitudinal Analysis Reveals Early Development of Three MPER-Directed Neutralizing Antibody Lineages from an HIV-1-Infected Individual. Immunity
Corbett KS, Moin SM, Yassine HM, et al. (2019) Design of Nanoparticulate Group 2 Influenza Virus Hemagglutinin Stem Antigens That Activate Unmutated Ancestor B Cell Receptors of Broadly Neutralizing Antibody Lineages. Mbio. 10
Vander Heiden JA, Marquez S, Marthandan N, et al. (2018) AIRR Community Standardized Representations for Annotated Immune Repertoires. Frontiers in Immunology. 9: 2206
Johnson EL, Doria-Rose NA, Gorman J, et al. (2018) Sequencing HIV-neutralizing antibody exons and introns reveals detailed aspects of lineage maturation. Nature Communications. 9: 4136
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