Prashanti Madhavapeddi, Ph.D.
Affiliations: | 2002 | University of Michigan, Ann Arbor, Ann Arbor, MI |
Area:
enzymology and protein designGoogle:
"Prashanti Madhavapeddi"Mean distance: 9.35 | S | N | B | C | P |
Parents
Sign in to add mentor| E. Neil G. Marsh | grad student | 2002 | University of Michigan | |
| (Identifying the active site of adenosylcobalamin-dependent glutamate mutase.) | ||||
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Publications
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| Naik M, Humnabadkar V, Tantry SJ, et al. (2014) 4-aminoquinolone piperidine amides: noncovalent inhibitors of DprE1 with long residence time and potent antimycobacterial activity. Journal of Medicinal Chemistry. 57: 5419-34 |
| Shirude PS, Madhavapeddi P, Naik M, et al. (2013) Methyl-thiazoles: a novel mode of inhibition with the potential to develop novel inhibitors targeting InhA in Mycobacterium tuberculosis. Journal of Medicinal Chemistry. 56: 8533-42 |
| Shirude PS, Madhavapeddi P, Tucker JA, et al. (2013) Aminopyrazinamides: novel and specific GyrB inhibitors that kill replicating and nonreplicating Mycobacterium tuberculosis. Acs Chemical Biology. 8: 519-23 |
| Madhavapeddi P, Ballou DP, Marsh ENG. (2002) Pre-steady-state kinetic studies on the Glu171Gln active site mutant of adenosylcobalamin-dependent glutamate mutase Biochemistry. 41: 15803-15809 |
| Madhavapeddi P, Marsh EN. (2001) The role of the active site glutamate in the rearrangement of glutamate to 3-methylaspartate catalyzed by adenosylcobalamin-dependent glutamate mutase. Chemistry & Biology. 8: 1143-9 |