David W. Konas, Ph.D.
Affiliations: | 2002 | University of Michigan, Ann Arbor, Ann Arbor, MI |
Area:
design potent and specific "mechanism-based inhibitors" of selected target enzymes for use as drugs in the treatment of cancer and parasitic diseasesGoogle:
"David Konas"Mean distance: 9.39 | S | N | B | C | P |
Parents
Sign in to add mentor| James K. Coward | grad student | 2002 | University of Michigan | |
| (New syntheses of optically active fluoroamino acids and methods for their application to the study of gamma-glutamyl hydrolase and folylpoly-gamma-glutamate synthetase.) | ||||
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Publications
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| Konas DW, Seci D, Tamimi S. (2012) Synthesis of (L)-4-fluorotryptophan Synthetic Communications. 42: 144-152 |
| Panda K, Adak S, Konas D, et al. (2004) A conserved aspartate (Asp-1393) regulates NADPH reduction of neuronal nitric-oxide synthase: implications for catalysis. The Journal of Biological Chemistry. 279: 18323-33 |
| Konas DW, Pankuch JJ, Coward JK. (2002) The synthesis of (2S)-4,4-difluoroglutamyl γ-peptides based on Garner's aldehyde and fluoro-reformatsky chemistry Synthesis. 2616-2626 |
| Konas DW, Coward JK. (2001) Electrophilic fluorination of pyroglutamic acid derivatives: application of substrate-dependent reactivity and diastereoselectivity to the synthesis of optically active 4-fluoroglutamic acids. The Journal of Organic Chemistry. 66: 8831-42 |
| Konas DW, Coward JK. (1999) Synthesis of L-4,4-difluoroglutamic acid via electrophilic difluorination of a lactam. Organic Letters. 1: 2105-7 |