Carolyn D. Shomin, Ph.D.

Affiliations: 
2011 Pharmaceutical Sciences University of Arizona, Tucson, AZ 
Area:
Bioorganic Chemistry
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"Carolyn Shomin"
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Indraneel Ghosh grad student 2011 University of Arizona
 (A bivalent methodology for targeting protein kinases: Conjugating phage display selected cyclic peptides to staurosporine.)
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Publications

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Jester BW, Gaj A, Shomin CD, et al. (2012) Testing the promiscuity of commercial kinase inhibitors against the AGC kinase group using a split-luciferase screen. Journal of Medicinal Chemistry. 55: 1526-37
Shomin CD, Restituyo E, Cox KJ, et al. (2011) Selection of cyclic-peptide inhibitors targeting Aurora kinase A: problems and solutions. Bioorganic & Medicinal Chemistry. 19: 6743-9
Cox KJ, Shomin CD, Ghosh I. (2011) Tinkering outside the kinase ATP box: allosteric (type IV) and bivalent (type V) inhibitors of protein kinases. Future Medicinal Chemistry. 3: 29-43
Jester BW, Cox KJ, Gaj A, et al. (2010) A coiled-coil enabled split-luciferase three-hybrid system: applied toward profiling inhibitors of protein kinases. Journal of the American Chemical Society. 132: 11727-35
Shomin CD, Meyer SC, Ghosh I. (2009) Staurosporine tethered peptide ligands that target cAMP-dependent protein kinase (PKA): optimization and selectivity profiling. Bioorganic & Medicinal Chemistry. 17: 6196-202
Meyer SC, Shomin CD, Gaj T, et al. (2007) Tethering small molecules to a phage display library: discovery of a selective bivalent inhibitor of protein kinase A. Journal of the American Chemical Society. 129: 13812-3
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