Dileep Pulukkunat, Ph.D.

Affiliations: 
2008 Ohio State University, Columbus, Columbus, OH 
Area:
Structure and mechanism of action of ribonuclease P, a catalytic ribonucleoprotein (RNP) complex
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"Dileep Pulukkunat"
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Venkat Gopalan grad student 2008 Ohio State
 (Biochemical studies on archaeal ribonuclease P reveal thematic convergence in protein-facilitated RNA catalysis.)
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Publications

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Chen WY, Pulukkunat DK, Cho IM, et al. (2010) Dissecting functional cooperation among protein subunits in archaeal RNase P, a catalytic ribonucleoprotein complex. Nucleic Acids Research. 38: 8316-27
Xu Y, Amero CD, Pulukkunat DK, et al. (2009) Solution structure of an archaeal RNase P binary protein complex: formation of the 30-kDa complex between Pyrococcus furiosus RPP21 and RPP29 is accompanied by coupled protein folding and highlights critical features for protein-protein and protein-RNA interactions. Journal of Molecular Biology. 393: 1043-55
Pulukkunat DK, Gopalan V. (2008) Studies on Methanocaldococcus jannaschii RNase P reveal insights into the roles of RNA and protein cofactors in RNase P catalysis. Nucleic Acids Research. 36: 4172-80
Zhu Y, Pulukkunat DK, Li Y. (2007) Deciphering RNA structural diversity and systematic phylogeny from microbial metagenomes. Nucleic Acids Research. 35: 2283-94
Tsai HY, Pulukkunat DK, Woznick WK, et al. (2006) Functional reconstitution and characterization of Pyrococcus furiosus RNase P. Proceedings of the National Academy of Sciences of the United States of America. 103: 16147-52
Pulukkunat DK, Raj ML, Pattanayak D, et al. (2003) Exploring the potential of plant RNase P as a functional genomics tool. Methods in Molecular Biology (Clifton, N.J.). 236: 295-310
Raj ML, Pulukkunat DK, Reckard JF, et al. (2001) Cleavage of bipartite substrates by rice and maize ribonuclease P. Application to degradation of target mRNAs in plants. Plant Physiology. 125: 1187-90
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