Jeremy M. Beck, Ph.D.

Affiliations: 
2011 Chemistry Ohio State University, Columbus, Columbus, OH 
Area:
reaction mechanisms
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Christopher M. Hadad grad student 2011 Ohio State
 (Organophosphorus nerve agent chemistry; interactions of chemical warfare agents and their therapeutics with acetylcholinesterase.)
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Publications

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Franjesevic AJ, Sillart SB, Beck JM, et al. (2019) Frontispiece: Resurrection and Reactivation of Acetylcholinesterase and Butyrylcholinesterase Chemistry – a European Journal. 25
Franjesevic AJ, Sillart SB, Beck JM, et al. (2018) Resurrection and Reactivation of Acetylcholinesterase and Butyrylcholinesterase. Chemistry (Weinheim An Der Bergstrasse, Germany)
Yoder RJ, Zhuang Q, Beck JM, et al. (2017) Study of para-Quinone Methide Precursors toward the Realkylation of Aged Acetylcholinesterase. Acs Medicinal Chemistry Letters. 8: 622-627
Beck JM, Miller SM, Peczuh MW, et al. (2012) C2 hydroxyl group governs the difference in hydrolysis rates of methyl-α-D-glycero-D-guloseptanoside and methyl-β-D-glycero-D-guloseptanoside. The Journal of Organic Chemistry. 77: 4242-51
Sanan TT, Muthukrishnan S, Beck JM, et al. (2010) Computational Modeling of Human Paraoxonase 1: Preparation of Protein Models, Binding Studies, and Mechanistic Insights. Journal of Physical Organic Chemistry. 23: 357-369
Vyas S, Beck JM, Xia S, et al. (2010) Butyrylcholinesterase and G116H, G116S, G117H, G117N, E197Q and G117H/E197Q mutants: a molecular dynamics study. Chemico-Biological Interactions. 187: 241-5
Beck JM, Hadad CM. (2010) Reaction profiles of the interaction between sarin and acetylcholinesterase and the S203C mutant: model nucleophiles and QM/MM potential energy surfaces. Chemico-Biological Interactions. 187: 220-4
Barakat NH, Zheng X, Gilley CB, et al. (2009) Chemical synthesis of two series of nerve agent model compounds and their stereoselective interaction with human acetylcholinesterase and human butyrylcholinesterase. Chemical Research in Toxicology. 22: 1669-79
Beck JM, Hadad CM. (2008) Hydrolysis of nerve agents by model nucleophiles: a computational study. Chemico-Biological Interactions. 175: 200-3
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