Ashley C. Gucinski, Ph.D.

Affiliations: 
2011 Chemistry University of Arizona, Tucson, AZ 
Area:
Bioanalytical Mass Spectrometry/Peptide and Protein Sequencing/ Ion-Surface Collisions/Large Protein-Protein Complexes/Biodefense/Proteomics
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"Ashley Gucinski"
Mean distance: 9.38
 
SNBCP

Parents

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Vicki H. Wysocki grad student 2011 University of Arizona
 (Gas phase structural studies of peptide fragment ions: Structural insights into mass spectrometry fragmentation mechanisms.)
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Publications

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Zhou M, Gucinski AC, Boyne MT. (2015) Performance metrics for evaluating system suitability in liquid chromatography - mass spectrometry peptide mass mapping of protein therapeutics and monoclonal antibodies. Mabs. 0
Zeng K, Geerlof-Vidavisky I, Gucinski A, et al. (2015) Liquid Chromatography-High Resolution Mass Spectrometry for Peptide Drug Quality Control. The Aaps Journal. 17: 643-51
Ye H, Hill J, Gucinski AC, et al. (2015) Direct site-specific glycoform identification and quantitative comparison of glycoprotein therapeutics: imiglucerase and velaglucerase alfa. The Aaps Journal. 17: 405-15
Gucinski AC, Boyne MT, Keire DA. (2015) Modern analytics for naturally derived complex drug substances: NMR and MS tests for protamine sulfate from chum salmon. Analytical and Bioanalytical Chemistry. 407: 749-59
Gucinski AC, Boyne MT. (2014) Identification of site-specific heterogeneity in peptide drugs using intact mass spectrometry with electron transfer dissociation. Rapid Communications in Mass Spectrometry : Rcm. 28: 1757-63
Levy MJ, Gucinski AC, Sommers CD, et al. (2014) Analytical techniques and bioactivity assays to compare the structure and function of filgrastim (granulocyte-colony stimulating factor) therapeutics from different manufacturers. Analytical and Bioanalytical Chemistry. 406: 6559-67
Mans DJ, Gucinski AC, Dunn JD, et al. (2013) Rapid screening and structural elucidation of a novel sibutramine analogue in a weight loss supplement: 11-desisobutyl-11-benzylsibutramine. Journal of Pharmaceutical and Biomedical Analysis. 83: 122-8
Wang B, Gucinski AC, Keire DA, et al. (2013) Structural comparison of two anti-CD20 monoclonal antibody drug products using middle-down mass spectrometry. The Analyst. 138: 3058-65
Gucinski AC, Chamot-Rooke J, Steinmetz V, et al. (2013) Influence of N-terminal residue composition on the structure of proline-containing b2+ ions. The Journal of Physical Chemistry. A. 117: 1291-8
Gucinski AC, Boyne MT. (2012) Evaluation of intact mass spectrometry for the quantitative analysis of protein therapeutics. Analytical Chemistry. 84: 8045-51
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