David J. Vocadlo, Ph.D.
Affiliations: | Chemistry | Simon Fraser University, Burnaby, British Columbia, Canada | |
| 2002 | University of British Columbia, Vancouver, Vancouver, BC, Canada |
Area:
enzyme mechanisms, protein structure/function relationships, enzyme inhibitor design/synthesis and protein engineeringWebsite:
https://www.sfu.ca/chemistry/people/profiles/dvocadlo/Google:
"David Vocadlo"Mean distance: 9.45 | S | N | B | C | P |
Parents
Sign in to add mentor| Stephen G. Withers | grad student | 2002 | UBC | |
| (The catalytic mechanism of retaining beta -glycosidases.) | ||||
Children
Sign in to add trainee| Samy Cecioni | grad student | ||
| Peter Sidhu | grad student | Simon Fraser | |
| Wesley F Zandberg | post-doc |
BETA: Related publications
See more...
Publications
|
You can help our author matching system! If you notice any publications incorrectly attributed to this author, please sign in and mark matches as correct or incorrect. |
| Calvelo M, Males A, Alteen MG, et al. (2023) Human -GlcNAcase Uses a Preactivated Boat-skew Substrate Conformation for Catalysis. Evidence from X-ray Crystallography and QM/MM Metadynamics. Acs Catalysis. 13: 13672-13678 |
| Pratt MR, Vocadlo DJ. (2023) Understanding and exploiting the roles of O-GlcNAc in neurodegenerative diseases. The Journal of Biological Chemistry. 299: 105411 |
| Escobar EE, Seeley EH, Serrano-Negrón JE, et al. (2023) In Situ Imaging of O-Linked β-N-Acetylglucosamine Using On-Tissue Hydrolysis and MALDI Mass Spectrometry. Cancers. 15 |
| Doherty GG, Ler GJM, Wimmer N, et al. (2022) Synthesis of Uronic Acid 1-Azasugars as Putative Inhibitors of α-Iduronidase, β-Glucuronidase and Heparanase. Chembiochem : a European Journal of Chemical Biology |
| Meek RW, Brockerman J, Fordwour OB, et al. (2022) The primary familial brain calcification-associated protein MYORG is an α-galactosidase with restricted substrate specificity. Plos Biology. 20: e3001764 |
| Santana A, Robinson K, Vickers C, et al. (2022) Pharmacological Chaperones for GCase That Switch Conformation with pH Enhance Enzyme Levels in Gaucher Animal Models. Angewandte Chemie (International Ed. in English) |
| King DT, Serrano-Negrón JE, Zhu Y, et al. (2022) Thermal Proteome Profiling Reveals the O-GlcNAc-Dependent Meltome. Journal of the American Chemical Society |
| Cecioni S, Ashmus RA, Gilormini PA, et al. (2022) Quantifying lysosomal glycosidase activity within cells using bis-acetal substrates. Nature Chemical Biology |
| Ahmed O, Affar M, Masclef L, et al. (2022) Immunoprecipitation and Western blot-based detection of protein O-GlcNAcylation in cells. Star Protocols. 3: 101108 |
| González-Cuesta M, Sidhu P, Ashmus RA, et al. (2022) Bicyclic Picomolar OGA Inhibitors Enable Chemoproteomic Mapping of Its Endogenous Post-translational Modifications. Journal of the American Chemical Society. 144: 832-844 |