Eric M. LeProust, Ph.D.

Affiliations: 
2001 University of Houston, Houston, TX, United States 
Area:
Biological NMR of Nucleic Acids and Proteins; Microarray BIOCHIP Technologies
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"Eric LeProust"
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Xiaolian Gao grad student 2001 University of Houston
 (Parallel synthesis of oligonucleotide microarrays using photogenerated acids and digital photolithography, and investigation of DNA synthesis fidelity on flat solid surfaces.)
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Publications

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Kosuri S, Eroshenko N, Leproust EM, et al. (2010) Scalable gene synthesis by selective amplification of DNA pools from high-fidelity microchips. Nature Biotechnology. 28: 1295-9
LeProust EM, Peck BJ, Spirin K, et al. (2010) Synthesis of high-quality libraries of long (150mer) oligonucleotides by a novel depurination controlled process. Nucleic Acids Research. 38: 2522-40
Cleary MA, Kilian K, Wang Y, et al. (2004) Production of complex nucleic acid libraries using highly parallel in situ oligonucleotide synthesis. Nature Methods. 1: 241-8
Srivannavit O, Gulari M, Gulari E, et al. (2004) Design and fabrication of microwell array chips for a solution-based, photogenerated acid-catalyzed parallel oligonuclotide DNA synthesis Sensors and Actuators, a: Physical. 116: 150-160
Gao X, LeProust E, Zhang H, et al. (2001) A flexible light-directed DNA chip synthesis gated by deprotection using solution photogenerated acids. Nucleic Acids Research. 29: 4744-50
LeProust E, Zhang H, Yu P, et al. (2001) Characterization of oligodeoxyribonucleotide synthesis on glass plates Nucleic Acids Research. 29: 2171-2180
LeProust EM, Pearson CE, Sinden RR, et al. (2000) Unexpected formation of parallel duplex in GAA and TTC trinucleotide repeats of Friedreich's ataxia. Journal of Molecular Biology. 302: 1063-80
LeProust E, Pellois JP, Yu P, et al. (2000) Digital light-directed synthesis. A microarray platform that permits rapid reaction optimization on a combinatorial basis. Journal of Combinatorial Chemistry. 2: 349-54
Zhou X, Gao X, LeProust E, et al. (1999) Light-directed, programmable microarray synthesis Nature Genetics. 23: 84-84
Gao X, Yu P, LeProust E, et al. (1998) Oligonucleotide synthesis using solution photogenerated acids [17] Journal of the American Chemical Society. 120: 12698-12699
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