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Larry D. Williams, Ph.D.

Affiliations: 
2008 Virginia Polytechnic Institute and State University, Blacksburg, VA, United States 
Area:
Stereoselective synthesis, medicinal chemistry
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"Larry Williams"
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Paul R. Carlier grad student 2008 Virginia Tech
 (Experimental and Computational Investigation of Tacrine-Based Inhibitors of Acetylcholinesterase.)

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Publications

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Ma M, Mehta J, Williams LD, et al. (2011) Pd-catalyzed amination as an alternative to nucleophilic aromatic substitution for the synthesis of N-alkyltacrines and analogues. Tetrahedron Letters. 52: 916-919
Rydberg EH, Brumshtein B, Greenblatt HM, et al. (2006) Complexes of alkylene-linked tacrine dimers with Torpedo californica acetylcholinesterase: Binding of Bis5-tacrine produces a dramatic rearrangement in the active-site gorge. Journal of Medicinal Chemistry. 49: 5491-500
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