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Orlando D. Schärer

Affiliations: 
Chemistry Stony Brook University, Stony Brook, NY, United States 
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"Orlando Schärer"
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The V. Ho grad student 2009 SUNY Stony Brook
Angelo Guainazzi grad student 2010 SUNY Stony Brook
Barbara Orelli grad student 2010 SUNY Stony Brook
Adebanke F. Fagbemi grad student 2011 SUNY Stony Brook
Jung-Eun Yeo grad student 2011 SUNY Stony Brook
Jerome Gualbert grad student 2012 SUNY Stony Brook
Yan Su grad student 2012 SUNY Stony Brook
Shivam Mukherjee grad student 2014 SUNY Stony Brook
Jawad Alzeer research scientist 2000-2010 Universität Zürich

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Publications

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Son K, Takhaveev V, Mor V, et al. (2024) Trabectedin derails transcription-coupled nucleotide excision repair to induce DNA breaks in highly transcribed genes. Nature Communications. 15: 1388
Slyskova J, Muniesa-Vargas A, da Silva IT, et al. (2023) Detection of oxaliplatin- and cisplatin-DNA lesions requires different global genome repair mechanisms that affect their clinical efficacy. Nar Cancer. 5: zcad057
Wie M, Khim KW, Groehler Iv AS, et al. (2023) Alkylation of nucleobases by 2-chloro--diethylethanamine hydrochloride (CDEAH) sensitizes -deficient tumors. Nar Cancer. 5: zcad042
Blee AM, Gallagher KS, Kim HS, et al. (2023) XPA tumor variants lead to defects in NER that sensitize cells to cisplatin. Biorxiv : the Preprint Server For Biology
Groehler AS, Maratova A, Dao NM, et al. (2023) Development of Comprehensive Ultraperformance Liquid Chromatography-High-Resolution Mass Spectrometry Assays to Quantitate Cisplatin-Induced DNA-DNA Cross-Links. Chemical Research in Toxicology
Oh JM, Kang Y, Park J, et al. (2023) MSH2-MSH3 promotes DNA end resection during homologous recombination and blocks polymerase theta-mediated end-joining through interaction with SMARCAD1 and EXO1. Nucleic Acids Research
van den Heuvel D, Kim M, Wondergem AP, et al. (2023) A disease-associated XPA allele interferes with TFIIH binding and primarily affects transcription-coupled nucleotide excision repair. Proceedings of the National Academy of Sciences of the United States of America. 120: e2208860120
Jaiswal AS, Kim HS, Schärer OD, et al. (2023) EEPD1 promotes repair of oxidatively-stressed replication forks. Nar Cancer. 5: zcac044
Chung HJ, Lee JR, Kim TM, et al. (2023) ZNF212 promotes genomic integrity through direct interaction with TRAIP. Nucleic Acids Research
Yue Z, Wu F, Guo F, et al. (2022) Polycarcin V induces DNA-damage response and enables the profiling of DNA-binding proteins. National Science Review. 9: nwac046
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