Wenli Meng, Ph.D.

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2013 Chemistry Stony Brook University, Stony Brook, NY, United States 
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Daniel P. Raleigh grad student 2013 SUNY Stony Brook
 (The Role of the Unfolded State in the Folding of Globular Proteins.)
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Publications

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Clerico EM, Meng W, Pozhidaeva A, et al. (2019) Hsp70 molecular chaperones: multifunctional allosteric holding and unfolding machines. The Biochemical Journal. 476: 1653-1677
Meng W, Clerico EM, McArthur N, et al. (2018) Allosteric landscapes of eukaryotic cytoplasmic Hsp70s are shaped by evolutionary tuning of key interfaces. Proceedings of the National Academy of Sciences of the United States of America. 115: 11970-11975
Thakur AK, Meng W, Gierasch LM. (2018) Local and non-local topological information in the denatured state ensemble of a β-barrel protein. Protein Science : a Publication of the Protein Society
English CA, Sherman W, Meng W, et al. (2017) The Hsp70 interdomain linker is a dynamic switch that enables allosteric communication between two structured domains. The Journal of Biological Chemistry
Clerico EM, Tilitsky JM, Meng W, et al. (2015) How hsp70 molecular machines interact with their substrates to mediate diverse physiological functions. Journal of Molecular Biology. 427: 1575-88
Cho JH, Meng W, Sato S, et al. (2014) Energetically significant networks of coupled interactions within an unfolded protein. Proceedings of the National Academy of Sciences of the United States of America. 111: 12079-84
Meng W, Luan B, Lyle N, et al. (2013) The denatured state ensemble contains significant local and long-range structure under native conditions: analysis of the N-terminal domain of ribosomal protein L9. Biochemistry. 52: 2662-71
Meng W, Lyle N, Luan B, et al. (2013) Experiments and simulations show how long-range contacts can form in expanded unfolded proteins with negligible secondary structure. Proceedings of the National Academy of Sciences of the United States of America. 110: 2123-8
Lyle NJ, Meng W, Raleigh DP, et al. (2012) Simulations of Denatured Protein Ensembles Reproduce and Rationalize Experimental Observations of Persistent Contacts Between Residues Distal in Protein Sequence Biophysical Journal. 102: 630a
Meng W, Raleigh DP. (2011) Analysis of electrostatic interactions in the denatured state ensemble of the N-terminal domain of L9 under native conditions. Proteins. 79: 3500-10
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