Richard Brust, Ph.D.
Affiliations: | 2013 | Chemistry | Stony Brook University, Stony Brook, NY, United States |
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"Richard Brust"Mean distance: 2949.11
Parents
Sign in to add mentorPeter J. Tonge | grad student | 2013 | SUNY Stony Brook | |
(Molecular Movie Magic: Real-time Picosecond to Microsecond Structural Dynamics of Photoactive Flavoproteins.) |
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Publications
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Shang J, Mosure SA, Zheng J, et al. (2020) A molecular switch regulating transcriptional repression and activation of PPAR gamma. Nature Communications. 11: 956-956 |
Mosure S, Shang J, Eberhardt J, et al. (2019) Structural basis of altered potency and efficacy displayed by a major in vivo metabolite of the anti-diabetic PPARγ drug pioglitazone. Journal of Medicinal Chemistry |
Brust R, Shang J, Fuhrmann J, et al. (2018) A structural mechanism for directing corepressor-selective inverse agonism of PPARγ. Nature Communications. 9: 4687 |
Zheng J, Corzo C, Chang MR, et al. (2018) Chemical Crosslinking Mass Spectrometry Reveals the Conformational Landscape of the Activation Helix of PPARγ; a Model for Ligand-Dependent Antagonism. Structure (London, England : 1993) |
Gil AA, Laptenok SP, Iuliano JN, et al. (2017) Photoactivation of the BLUF protein PixD Probed by the Site-Specific Incorporation of Fluorotyrosine Residues. Journal of the American Chemical Society |
Hughes TS, Shang J, Brust R, et al. (2016) Probing the Complex Binding Modes of the PPARγ Partial Agonist 2-chloro-N-(3-chloro-4-((5-chlorobenzo[d]thiazol-2-yl)thio)phenyl)-4-(trifluoromethyl)benzenesulfonamide (T2384) to Orthosteric and Allosteric Sites with NMR Spectroscopy. Journal of Medicinal Chemistry |
Gil AA, Haigney AL, Laptenok SP, et al. (2015) The Mechanism of the AppABLUF Photocycle Probed by Site-Specific Incorporation of Fluorotyrosine Residues: The Effect of the Y21 pKa on the Forward and Reverse Ground State Reactions. Journal of the American Chemical Society |
Laptenok SP, Lukacs A, Gil A, et al. (2015) Complete Proton Transfer Cycle in GFP and Its T203V and S205V Mutants. Angewandte Chemie (International Ed. in English). 54: 9303-7 |
Laptenok SP, Lukacs A, Brust R, et al. (2015) Electron transfer quenching in light adapted and mutant forms of the AppA BLUF domain. Faraday Discussions. 177: 293-311 |
Brust R, Haigney A, Lukacs A, et al. (2014) Ultrafast Structural Dynamics of BlsA, a Photoreceptor from the Pathogenic Bacterium Acinetobacter baumannii. The Journal of Physical Chemistry Letters. 5: 220-224 |