Yue-Lei Chen

Affiliations: 
University of Minnesota, Twin Cities, Minneapolis, MN 
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"Yue-Lei Chen"
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Publications

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Wang X, Su M, Li Y, et al. (2019) Tranylcypromine and 6-trifluoroethyl thienopyrimidine hybrid as LSD1 inhibitor. Bioorganic & Medicinal Chemistry Letters
Liu T, Tang J, Liang J, et al. (2019) Stereoselective N-glycosylation with N4-acyl cytosines and efficient synthesis of gemcitabine Tetrahedron. 75: 1203-1213
Hu J, Wang Y, Li Y, et al. (2018) Structure-based optimization of a series of selective BET inhibitors containing aniline or indoline groups. European Journal of Medicinal Chemistry. 150: 156-175
Liu T, Zhu Z, Ren H, et al. (2018) Efficient syntheses of alpha- and beta-C-nucleosides and the origin of anomeric selectivity Organic Chemistry Frontiers. 5: 1992-1999
Liu T, Ren H, Li C, et al. (2018) Convenient preparation of pinometostat and related 5′-deoxy-5′-amino adenosine derivatives as well as their activity against DOT1L Tetrahedron Letters. 59: 415-417
Liu T, Xie W, Li C, et al. (2017) Preparation of 5'-deoxy-5'-amino-5'-C-methyl adenosine derivatives and their activity against DOT1L. Bioorganic & Medicinal Chemistry Letters
Kirby KA, Myshakina NA, Christen MT, et al. (2017) A 2-hydroxyisoquinoline-1,3-dione active site RNase H inhibitor binds in multiple modes to HIV-1 reverse transcriptase. Antimicrobial Agents and Chemotherapy
Hu J, Wang Y, Li Y, et al. (2017) Discovery of a series of dihydroquinoxalin-2(1H)-ones as selective BET inhibitors from a dual PLK1-BRD4 inhibitor. European Journal of Medicinal Chemistry. 137: 176-195
Tang J, Vernekar SK, Chen YL, et al. (2017) Synthesis, biological evaluation and molecular modeling of 2-Hydroxyisoquinoline-1,3-dione analogues as inhibitors of HIV reverse transcriptase associated ribonuclease H and polymerase. European Journal of Medicinal Chemistry. 133: 85-96
Li Y, Liu T, Li C, et al. (2017) A one-pot synthesis of omarigliptin and its analogues through stabilized beta-amino ketone intermediate Synthetic Communications. 47: 357-363
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