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Hans Kosterlitz

Affiliations: 
University of Aberdeen, Aberdeen, Scotland, United Kingdom 
Area:
Enkephalin
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"Hans Kosterlitz"
Bio:

"In 1975 Hans Kosterlitz and his colleagues reported the existence of an endogenous morphine-like substance. Later, they purified their discovery after a two year investigation of pig-brain materials. They named it enkephalin for "in the head".

Mean distance: 14.96 (cluster 11)
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Parents

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Otto Krayer research scientist 1953-1954 Harvard Medical School

Children

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Frances M. Leslie grad student UC Irvine
Graeme Henderson grad student 1973 University of Aberdeen
R Alan North grad student 1973 University of Aberdeen
Gordon M Lees post-doc University of Aberdeen

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Publications

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Henderson G, Hughes J, Kosterlitz HW. (1997) A new example of a morphine-sensitive neuro-effector junction: adrenergic transmission in the mouse vas deferens. 1972. British Journal of Pharmacology. 120: 396-8; discussion 39
Kosterlitz HW, Paterson SJ, Robson LE. (1988) Modulation of binding at opioid receptors by mono- and divalent cations and by cholinergic compounds. Journal of Receptor Research. 8: 363-73
Kosterlitz HW, Paterson SJ, Robson LE, et al. (1987) Effects of cations on binding, in membrane suspensions, of various opioids at mu-sites of rabbit cerebellum and kappa-sites of guinea-pig cerebellum. British Journal of Pharmacology. 91: 431-7
Waterfield AA, Leslie FM, Lord JA, et al. (1979) Opioid activities of fragments of beta-endorphin and of its leucine65-analogue. Comparison of the binding properties of methionine- and leucine-enkephalin. European Journal of Pharmacology. 58: 11-8
Leslie FM, Kosterlitz HW. (1979) Comparison of binding of [3H]-methionine-enkephalin, [3H]-naltrexone and [3H]-dihydromorphine in the mouse vas deferens and the myenteric plexus and brain of the ginea pig. European Journal of Pharmacology. 56: 379-83
Gillan MG, Kosterlitz HW, Robson LE, et al. (1979) The inhibitory effects of presynaptic alpha-adrenoceptor agonists on contractions of guinea-pig ileum and mouse vas deferens in the morphine-dependent and withdrawn states produced in vitro. British Journal of Pharmacology. 66: 601-8
Kosterlitz HW, Leslie FM. (1978) Comparison of the receptor binding characteristics of opiate agonists interacting with mu- or kappa-receptors. British Journal of Pharmacology. 64: 607-14
Henderson G, Hughes J, Kosterlitz HW. (1978) In vitro release of Leu- and Met-enkephalin from the corpus striatum. Nature. 271: 677-9
Kosterlitz HW, Leslie FM. (1977) Inhibition of [3H]-naloxone binding by opiate agonists [proceedings]. British Journal of Pharmacology. 59: 478P
Lord JA, Waterfield AA, Hughes J, et al. (1977) Endogenous opioid peptides: multiple agonists and receptors. Nature. 267: 495-9
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