Brian S. Majors, Ph.D.
Affiliations: | 2009 | Johns Hopkins University, Baltimore, MD |
Area:
Chemical Engineering, Cell BiologyGoogle:
"Brian Majors"Mean distance: 4190.84
Parents
Sign in to add mentor| Michael J. Betenbaugh | grad student | 2009 | Johns Hopkins | |
| (Cellular engineering strategies for improvement of mammalian cell phenotypes in commercial applications.) | ||||
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Publications
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| Majors BS, Chiang GG, Pederson NE, et al. (2012) Directed evolution of mammalian anti-apoptosis proteins by somatic hypermutation. Protein Engineering, Design & Selection : Peds. 25: 27-38 |
| Druz A, Chu C, Majors B, et al. (2011) A novel microRNA mmu-miR-466h affects apoptosis regulation in mammalian cells. Biotechnology and Bioengineering. 108: 1651-61 |
| Majors BS, Betenbaugh MJ, Pederson NE, et al. (2009) Mcl-1 overexpression leads to higher viabilities and increased production of humanized monoclonal antibody in Chinese hamster ovary cells. Biotechnology Progress. 25: 1161-8 |
| O'Connor S, Li E, Majors BS, et al. (2009) Increased expression of the integral membrane protein ErbB2 in Chinese hamster ovary cells expressing the anti-apoptotic gene Bcl-xL. Protein Expression and Purification. 67: 41-7 |
| Majors BS, Chiang GG, Betenbaugh MJ. (2009) Protein and genome evolution in Mammalian cells for biotechnology applications. Molecular Biotechnology. 42: 216-23 |
| Majors BS, Arden N, Oyler GA, et al. (2008) E2F-1 overexpression increases viable cell density in batch cultures of Chinese hamster ovary cells. Journal of Biotechnology. 138: 103-6 |
| Majors BS, Betenbaugh MJ, Pederson NE, et al. (2008) Enhancement of transient gene expression and culture viability using Chinese hamster ovary cells overexpressing Bcl-x(L). Biotechnology and Bioengineering. 101: 567-78 |
| Majors BS, Betenbaugh MJ, Chiang GG. (2007) Links between metabolism and apoptosis in mammalian cells: applications for anti-apoptosis engineering. Metabolic Engineering. 9: 317-26 |
| Arden N, Majors BS, Ahn SH, et al. (2007) Inhibiting the apoptosis pathway using MDM2 in mammalian cell cultures. Biotechnology and Bioengineering. 97: 601-14 |