Giordano F. Da Silva, Ph.D.

Affiliations: 
2007 University of South Florida, Tampa, FL, United States 
Area:
Biochemistry, Inorganic Chemistry
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"Giordano Da Silva"
Mean distance: 8847.33
 

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Li-June Ming grad student 2007 University of South Florida
 (The bioinorganic chemistry of copper -containing systems: From type-3 systems pertinent to Alzheimer's disease to mononuclear hydrolysis involved in biological development.)
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Publications

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Tay WM, da Silva GF, Ming LJ. (2013) Metal binding of flavonoids and their distinct inhibition mechanisms toward the oxidation activity of Cu2+-β-amyloid: not just serving as suicide antioxidants! Inorganic Chemistry. 52: 679-90
Tay WM, Epperson JD, da Silva GF, et al. (2010) 1H NMR, mechanism, and mononuclear oxidative activity of the antibiotic metallopeptide bacitracin: the role of D-Glu-4, interaction with pyrophosphate moiety, DNA binding and cleavage, and bioactivity. Journal of the American Chemical Society. 132: 5652-61
da Silva GF, Lykourinou V, Angerhofer A, et al. (2009) Methionine does not reduce Cu(II)-beta-amyloid!--rectification of the roles of methionine-35 and reducing agents in metal-centered oxidation chemistry of Cu(II)-beta-amyloid. Biochimica Et Biophysica Acta. 1792: 49-55
da Silva GF, Ming LJ. (2007) Metallo-ROS in Alzheimer's disease: oxidation of neurotransmitters by CuII-beta-amyloid and neuropathology of the disease. Angewandte Chemie (International Ed. in English). 46: 3337-41
da Silva GF, Reuille RL, Ming LJ, et al. (2006) Overexpression and mechanistic characterization of blastula protease 10, a metalloprotease involved in sea urchin embryogenesis and development. The Journal of Biological Chemistry. 281: 10737-44
da Silva GF, Ming LJ. (2005) Catechol oxidase activity of di-Cu2+-substituted aminopeptidase from Streptomyces griseus. Journal of the American Chemical Society. 127: 16380-1
da Silva GF, Ming LJ. (2005) Alzheimer's disease related copper(II)- beta-amyloid peptide exhibits phenol monooxygenase and catechol oxidase activities. Angewandte Chemie (International Ed. in English). 44: 5501-4
da Silva GF, Tay WM, Ming LJ. (2005) Catechol oxidase-like oxidation chemistry of the 1-20 and 1-16 fragments of Alzheimer's disease-related beta-amyloid peptide: their structure-activity correlation and the fate of hydrogen peroxide. The Journal of Biological Chemistry. 280: 16601-9
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