Andreas Papoutsis, Ph.D.

Affiliations: 
2012 Nutritional Sciences University of Arizona, Tucson, AZ 
Area:
Nutrition, Oncology, Molecular Biology
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"Andreas Papoutsis"
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Parents

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Donato F. Romagnolo grad student 2012 University of Arizona
 (Epigenetic regulation of breast cancer type-1 gene by the activated aromatic hydrocarbon receptor and the preventative effects of resveratrol.)
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Publications

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Selmin OI, Papoutsis AJ, Hazan S, et al. (2021) -6 High Fat Diet Induces Gut Microbiome Dysbiosis and Colonic Inflammation. International Journal of Molecular Sciences. 22
Romagnolo DF, Donovan MG, Papoutsis AJ, et al. (2017) Genistein Prevents CpG Methylation and Proliferation in Human Breast Cancer Cells with Activated Aromatic Hydrocarbon Receptor. Current Developments in Nutrition. 1: e000562
Romagnolo DF, Papoutsis AJ, Laukaitis C, et al. (2015) Constitutive expression of AhR and BRCA-1 promoter CpG hypermethylation as biomarkers of ERα-negative breast tumorigenesis. Bmc Cancer. 15: 1026
Papoutsis AJ, Selmin OI, Borg JL, et al. (2015) Gestational exposure to the AhR agonist 2,3,7,8-tetrachlorodibenzo-p-dioxin induces BRCA-1 promoter hypermethylation and reduces BRCA-1 expression in mammary tissue of rat offspring: preventive effects of resveratrol. Molecular Carcinogenesis. 54: 261-9
Papoutsis AJ, Borg JL, Selmin OI, et al. (2012) BRCA-1 promoter hypermethylation and silencing induced by the aromatic hydrocarbon receptor-ligand TCDD are prevented by resveratrol in MCF-7 cells. The Journal of Nutritional Biochemistry. 23: 1324-32
Palbykin B, Borg J, Caldwell PT, et al. (2011) Trichloroethylene induces methylation of the Serca2 promoter in H9c2 cells and embryonic heart. Cardiovascular Toxicology. 11: 204-14
Papoutsis AJ, Lamore SD, Wondrak GT, et al. (2010) Resveratrol prevents epigenetic silencing of BRCA-1 by the aromatic hydrocarbon receptor in human breast cancer cells. The Journal of Nutrition. 140: 1607-14
Romagnolo DF, Papoutsis AJ, Selmin O. (2010) Nutritional targeting of cyclooxygenase-2 for colon cancer prevention. Inflammation & Allergy Drug Targets. 9: 181-91
Degner SC, Papoutsis AJ, Selmin O, et al. (2009) Targeting of aryl hydrocarbon receptor-mediated activation of cyclooxygenase-2 expression by the indole-3-carbinol metabolite 3,3'-diindolylmethane in breast cancer cells. The Journal of Nutrition. 139: 26-32
Degner SC, Papoutsis AJ, Romagnolo DF. (2009) Health Benefits of Traditional culinary and Medicinal Mediterranean Plants Complementary and Alternative Therapies and the Aging Population. 541-562
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