Irving M. Shapiro

Affiliations: 
University of Pennsylvania, Philadelphia, PA, United States 
Area:
Cell Biology, Molecular Biology, Biochemistry
Website:
https://www.jefferson.edu/academics/colleges-schools-institutes/life-sciences/faculty-staff/faculty/shapiro.html
Google:
"Irving M. Shapiro"
Bio:

Shapiro, Irving M. The Association of Phospholipids with Mineralised Tissues. PhD diss., University of London, 1968.

Mean distance: 19906.5
 

Children

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Ahmed El-Ghannam grad student 1995 Penn (E-Tree)
Cristina M. Teixeira grad student 2001 Penn
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Publications

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Madhu V, Boneski PK, Silagi E, et al. (2020) Hypoxic regulation of mitochondrial metabolism and mitophagy in nucleus pulposus cells is dependent on HIF-1α -BNIP3 axis. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research
Tessier S, Doolittle AC, Sao K, et al. (2020) Arp2/3 inactivation causes intervertebral disc and cartilage degeneration with dysregulated TonEBP-mediated osmoadaptation. Jci Insight
Gorth DJ, Ottone OK, Shapiro IM, et al. (2019) Differential effect of long-term systemic exposure of TNFα on health of the annulus fibrosus and nucleus pulposus of the intervertebral disc. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research
Tessier S, Tran VA, Ottone OK, et al. (2019) TonEBP-deficiency accelerates intervertebral disc degeneration underscored by matrix remodeling, cytoskeletal rearrangements, and changes in proinflammatory gene expression. Matrix Biology : Journal of the International Society For Matrix Biology
Silagi ES, Novais EJ, Bisetto S, et al. (2019) Lactate Efflux from Intervertebral Disc Cells is Required for Maintenance of Spine Health. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research
Choi H, Madhu V, Shapiro IM, et al. (2019) Nucleus pulposus primary cilia alter their length in response to changes in extracellular osmolarity but do not control TonEBP-mediated osmoregulation. Scientific Reports. 9: 15469
Tessier S, Madhu V, Johnson ZI, et al. (2019) NFAT5/TonEBP controls early acquisition of notochord phenotypic markers, collagen composition, and sonic hedgehog signaling during mouse intervertebral disc embryogenesis. Developmental Biology
Novais EM, Diekman BO, Shapiro IM, et al. (2019) p16 deletion in cells of the intervertebral disc affects their matrix homeostasis and senescence associated secretory phenotype without altering onset of senescence. Matrix Biology : Journal of the International Society For Matrix Biology
Gorth DJ, Shapiro IM, Risbud MV. (2018) Transgenic mice overexpressing human TNF-α experience early onset spontaneous intervertebral disc herniation in the absence of overt degeneration. Cell Death & Disease. 10: 7
Pan H, Strickland A, Madhu V, et al. (2018) RNA binding protein HuR regulates extracellular matrix gene expression and pH homeostasis independent of controlling HIF-1α signaling in nucleus pulposus cells. Matrix Biology : Journal of the International Society For Matrix Biology
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