Randolph Y. Hampton

Affiliations: 
University of California, San Diego, La Jolla, CA 
Area:
Cell Biology, Biochemistry
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"Randolph Hampton"
Mean distance: 3317.75
 

Children

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Stephen R. Cronin grad student 2001 UCSD
Nathan W. Bays grad student 2002 UCSD
Alexander G. Shearer grad student 2004 UCSD
Omar A. Bazirgan grad student 2007 UCSD
Jem A. Efe grad student 2007 UCSD
Christine M. Federovitch grad student 2007 UCSD
Jenny B. DuRose grad student 2008 UCSD
Renee M. Garza grad student 2008 UCSD
Brian K. Sato grad student 2008 UCSD
Sarah M. Carroll grad student 2010 UCSD
Jarrod W. Heck grad student 2010 UCSD
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Publications

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Flagg MP, Lam B, Lam DK, et al. (2023) Exploring the "misfolding problem" by systematic discovery and analysis of functional-but-degraded proteins. Molecular Biology of the Cell. 34: ar125
Flagg MP, Wangeline MA, Holland SR, et al. (2021) Inner-Nuclear-Membrane-Associated Degradation Employs Dfm1-Independent Retrotranslocation and Alleviates Misfolded Transmembrane-Protein Toxicity. Molecular Biology of the Cell. mbcE20110720
Wangeline MA, Hampton RY. (2020) An autonomous, but INSIG-modulated, role for the Sterol Sensing Domain in mallostery-regulated ERAD of yeast HMG-CoA reductase. The Journal of Biological Chemistry
Singh A, Vashistha N, Heck J, et al. (2020) Direct involvement of Hsp70 ATP hydrolysis in Ubr1-dependent quality control. Molecular Biology of the Cell. mbcE20080541
Neal S, Syau D, Nejatfard A, et al. (2020) HRD Complex Self-Remodeling Enables a Novel Route of Membrane Protein Retrotranslocation. Iscience. 23: 101493
Neal S, Duttke SH, Hampton RY. (2019) Assays for protein retrotranslocation in ERAD. Methods in Enzymology. 619: 1-26
Wangeline MA, Hampton RY. (2018) "Mallostery"-ligand-dependent protein misfolding enables physiological regulation by ERAD. The Journal of Biological Chemistry
Jaeger PA, Ornelas L, McElfresh C, et al. (2018) Systematic Gene-to-Phenotype Arrays: A High-Throughput Technique for Molecular Phenotyping. Molecular Cell. 69: 321-333.e3
Neal S, Jaeger PA, Duttke SH, et al. (2018) The Dfm1 Derlin Is Required for ERAD Retrotranslocation of Integral Membrane Proteins. Molecular Cell. 69: 306-320.e4
Wangeline MA, Vashistha N, Hampton RY. (2017) Proteostatic Tactics in the Strategy of Sterol Regulation. Annual Review of Cell and Developmental Biology. 33: 467-489
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