Donghak Kim, Ph.D.

Affiliations: 
2004 Vanderbilt University, Nashville, TN 
Area:
Biochemistry, Toxicology, Pharmacology
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"Donghak Kim"
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F Peter Guengerich grad student 2004 Vanderbilt
 (Analysis of enzymatic activities of human cytochromes P450 1A2 and 2A6 using mutagenesis.)
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Publications

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Nagayoshi H, Murayama N, Kim V, et al. (2023) Oxidation of Naringenin, Apigenin, and Genistein by Human Family 1 Cytochrome P450 Enzymes and Comparison of Interaction of Apigenin with Human P450 1B1.1 and Scutellaria P450 82D.1. Chemical Research in Toxicology
Lee YB, Kim V, Lee SG, et al. (2023) Functional Characterization of Allelic Variations of Human Cytochrome P450 2C8 (V181I, I244V, I331T, and L361F). International Journal of Molecular Sciences. 24
Lee SG, Kim V, Lee GH, et al. (2023) Hydroxylation and lyase reactions of steroids catalyzed by mouse cytochrome P450 17A1 (Cyp17a1). Journal of Inorganic Biochemistry. 240: 112085
Kim V, Kim D, Lee S, et al. (2022) Structural characterization and fatty acid epoxidation of CYP184A1 from Streptomyces avermitilis. Archives of Biochemistry and Biophysics. 109338
Shimada T, Nagayoshi H, Murayama N, et al. (2022) Oxidation of 3'-methoxyflavone, 4'-methoxyflavone, and 3',4'-dimethoxyflavone and their derivatives having 5,7-dihydroxyl moieties by human cytochromes P450 1B1 and 2A13. Xenobiotica; the Fate of Foreign Compounds in Biological Systems. 52: 134-145
Lee R, Kim V, Chun Y, et al. (2021) Structure-Functional Analysis of Human Cytochrome P450 2C8 Using Directed Evolution. Pharmaceutics. 13
Kim D, Kim V, Tateishi Y, et al. (2021) . Drug Metabolism and Disposition: the Biological Fate of Chemicals
Nagayoshi H, Murayama N, Takenaka S, et al. (2021) Roles of cytochrome P450 2A6 in the oxidation of flavone, 4´-hydroxyflavone, and 4´-, 3´-, and 2´-methoxyflavones by human liver microsomes. Xenobiotica; the Fate of Foreign Compounds in Biological Systems. 1-47
Kim D, Kim V, McCarty KD, et al. (2021) Tight binding of cytochrome b to cytochrome P450 17A1 is a critical feature of stimulation of C21 steroid lyase activity and androgen synthesis. The Journal of Biological Chemistry. 100571
Shimada T, Nagayoshi H, Murayama N, et al. (2020) Liquid chromatography-tandem mass spectrometry analysis of oxidation of 2´-, 3´-, 4´-, and 6-hydroxyflavanones by human cytochrome P450 enzymes. Xenobiotica; the Fate of Foreign Compounds in Biological Systems. 1-55
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