Edward J. Bilsky

Affiliations: 
Biological Sciences The University of Northern Colorado 
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"Edward Bilsky"
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Vekariya RH, Lei W, Ray A, et al. (2020) Synthesis and Structure-Activity Relationships of 5'-Aryl-14-alkoxypyridomorphinans: Identification of a Mu Opioid Receptor Agonist/Delta Opioid Receptor Antagonist Ligand with Systemic Antinociceptive Activity and Diminished Opioid Side Effects. Journal of Medicinal Chemistry
Stevenson GW, Giuvelis D, Cormier J, et al. (2020) Behavioral pharmacology of the mixed-action delta-selective opioid receptor agonist BBI-11008: studies on acute, inflammatory and neuropathic pain, respiration, and drug self-administration. Psychopharmacology
Streicher JM, Bilsky EJ. (2017) Peripherally Acting µ-Opioid Receptor Antagonists for the Treatment of Opioid-Related Side Effects: Mechanism of Action and Clinical Implications. Journal of Pharmacy Practice. 897190017732263
McLane VD, Bergquist I, Cormier J, et al. (2017) Long-term morphine delivery via slow release morphine pellets or osmotic pumps: Plasma concentration, analgesia, and naloxone-precipitated withdrawal. Life Sciences
Lei W, Mullen N, McCarthy S, et al. (2017) Heat shock protein 90 (Hsp90) promotes opioid-induced anti-nociception by an ERK Mitogen Activated Protein Kinase (MAPK) mechanism in mouse brain. The Journal of Biological Chemistry
Zhang Y, Williams DA, Zaidi SA, et al. (2015) 17-Cyclopropylmethyl-3,14β-dihydroxy-4,5α-epoxy-6β-(4'-pyridylcarboxamido)morphinan (NAP) modulating the mu opioid receptor in a biased fashion. Acs Chemical Neuroscience
Lefever M, Li Y, Anglin B, et al. (2015) Structural Requirements for CNS Active Opioid Glycopeptides. Journal of Medicinal Chemistry. 58: 5728-41
Stevenson GW, Luginbuhl A, Dunbar C, et al. (2015) The mixed-action delta/mu opioid agonist MMP-2200 does not produce conditioned place preference but does maintain drug self-administration in rats, and induces in vitro markers of tolerance and dependence. Pharmacology, Biochemistry, and Behavior. 132: 49-55
Zhang Y, Braithwaite A, Yuan Y, et al. (2014) Behavioral and cellular pharmacology characterization of 17-cyclopropylmethyl-3,14β-dihydroxy-4,5α-epoxy-6α-(isoquinoline-3'-carboxamido)morphinan (NAQ) as a mu opioid receptor selective ligand. European Journal of Pharmacology. 736: 124-30
Li Y, St Louis L, Knapp BI, et al. (2014) Can amphipathic helices influence the CNS antinociceptive activity of glycopeptides related to β-endorphin? Journal of Medicinal Chemistry. 57: 2237-46
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