Andrew S. Dutton, Ph.D.

Affiliations: 
2005 University of California, Los Angeles, Los Angeles, CA 
Area:
Organic Chemistry
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"Andrew Dutton"
Mean distance: 13271
 

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Jon Fukuto grad student 2005 UCLA
 (The theoretical chemistry and biochemistry of nitroxyl and nitric oxide and their NONOate donors.)
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Publications

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Jackson MI, Han TH, Serbulea L, et al. (2009) Kinetic feasibility of nitroxyl reduction by physiological reductants and biological implications. Free Radical Biology & Medicine. 47: 1130-9
Dutton AS, Suhrada CP, Miranda KM, et al. (2006) Mechanism of pH-dependent decomposition of monoalkylamine diazeniumdiolates to form HNO and NO, deduced from the model compound methylamine diazeniumdiolate, density functional theory, and CBS-QB3 calculations. Inorganic Chemistry. 45: 2448-56
Miranda KM, Katori T, Torres de Holding CL, et al. (2005) Comparison of the NO and HNO donating properties of diazeniumdiolates: primary amine adducts release HNO in Vivo. Journal of Medicinal Chemistry. 48: 8220-8
Dutton AS, Fukuto JM, Houk KN. (2005) Quantum mechanical determinations of reaction mechanisms, acid base, and redox properties of nitrogen oxides and their donors. Methods in Enzymology. 396: 26-44
Dutton AS, Fukuto JM, Houk KN. (2005) Theoretical reduction potentials for nitrogen oxides from CBS-QB3 energetics and (C)PCM solvation calculations. Inorganic Chemistry. 44: 4024-8
Fukuto JM, Bartberger MD, Dutton AS, et al. (2005) The physiological chemistry and biological activity of nitroxyl (HNO): the neglected, misunderstood, and enigmatic nitrogen oxide. Chemical Research in Toxicology. 18: 790-801
Miranda KM, Dutton AS, Ridnour LA, et al. (2005) Mechanism of aerobic decomposition of Angeli's salt (sodium trioxodinitrate) at physiological pH. Journal of the American Chemical Society. 127: 722-31
Fukuto JM, Dutton AS, Houk KN. (2005) The chemistry and biology of nitroxyl (HNO): a chemically unique species with novel and important biological activity. Chembiochem : a European Journal of Chemical Biology. 6: 612-9
Dutton AS, Fukuto JM, Houk KN. (2004) Mechanisms of HNO and NO production from Angeli's salt: density functional and CBS-QB3 theory predictions. Journal of the American Chemical Society. 126: 3795-800
Dutton AS, Fukuto JM, Houk KN. (2004) The mechanism of NO formation from the decomposition of dialkylamino diazeniumdiolates: density functional theory and CBS-QB3 predictions. Inorganic Chemistry. 43: 1039-45
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