Erik J. Sontheimer, Ph.D.

Affiliations: 
1999-2014 Molecular Biosciences Northwestern University, Evanston, IL 
 2014- RNA Therapeutics Institute University Of Massachusetts Med Sch Worcester 
Area:
RNA biology, CRISPR, genome editing
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"Erik Sontheimer"
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Children

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John Pham grad student 2000-2006 Cell, Cell Press
Priya Bellare grad student 2000-2007
Janice Pellino grad student 2001-2007
Zhengying He grad student 2002-2008
Jon Preall grad student 2004-2009 CSHL
Sara Layman grad student 2006-2014 Altria
Noelle Wakefield grad student 2007-2015 MIT
Luciano A. Marraffini post-doc 2008-2010 Rockefeller (Microtree)
R. Vincent Gerbasi post-doc 2007-2011 PNNL
Yan Zhang post-doc 2013-2016 University of Michigan Medical School Ann Arbor
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Publications

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Kraus C, Sontheimer EJ. (2023) Viruses use RNA decoys to thwart CRISPR defences. Nature. 623: 490-491
Liu B, Dong X, Cheng H, et al. (2022) A split prime editor with untethered reverse transcriptase and circular RNA template. Nature Biotechnology
Barrangou R, Sontheimer EJ. (2020) Shutting down RNA-targeting CRISPR. Science (New York, N.Y.). 369: 31-32
Gao XD, Rodríguez TC, Sontheimer EJ. (2019) Adapting dCas9-APEX2 for subnuclear proteomic profiling. Methods in Enzymology. 616: 365-383
Mir A, Alterman JF, Hassler MR, et al. (2018) Heavily and fully modified RNAs guide efficient SpyCas9-mediated genome editing. Nature Communications. 9: 2641
Sontheimer EJ, Marraffini LA. (2016) RNA. CRISPR goes retro. Science (New York, N.Y.). 351: 920-1
Zhang Y, Rajan R, Seifert HS, et al. (2015) DNase H Activity of Neisseria meningitidis Cas9. Molecular Cell. 60: 242-55
Wakefield N, Rajan R, Sontheimer EJ. (2015) Primary processing of CRISPR RNA by the endonuclease Cas6 in Staphylococcus epidermidis. Febs Letters. 589: 3197-204
Sontheimer EJ, Barrangou R. (2015) The Bacterial Origins of the CRISPR Genome-Editing Revolution. Human Gene Therapy. 26: 413-24
Hou Z, Zhang Y, Propson NE, et al. (2013) Efficient genome engineering in human pluripotent stem cells using Cas9 from Neisseria meningitidis. Proceedings of the National Academy of Sciences of the United States of America. 110: 15644-9
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