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Bryan W. Newman, Ph.D.

Affiliations: 
2012 University of Michigan, Ann Arbor, Ann Arbor, MI 
Area:
Pharmacy, Pharmacology, Medicine and Surgery, Oncology, Cell Biology
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"Bryan Newman"
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Duxin Sun grad student 2012 University of Michigan
 (17-AAG Mediated HSP90 Inhibition as an Effective Therapy for Lymphoma Stem Cells.)

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Publications

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Burnett JP, Korkaya H, Ouzounova MD, et al. (2015) Trastuzumab resistance induces EMT to transform HER2(+) PTEN(-) to a triple negative breast cancer that requires unique treatment options. Scientific Reports. 5: 15821
Burnett J, Korkaya H, Newman B, et al. (2013) Abstract 913: Natural product sulforaphane selectively inhibits breast cancer stem cells in basal and trastuzumab resistant Her2+ breast cancer. Cancer Research. 73: 913-913
Newman B, Liu Y, Lee HF, et al. (2012) HSP90 inhibitor 17-AAG selectively eradicates lymphoma stem cells. Cancer Research. 72: 4551-61
Burnett J, Newman B, Sun D. (2012) Targeting cancer stem cells with natural products. Current Drug Targets. 13: 1054-64
Conley SJ, Gheordunescu E, Kakarala P, et al. (2012) Antiangiogenic agents increase breast cancer stem cells via the generation of tumor hypoxia Proceedings of the National Academy of Sciences of the United States of America. 109: 2784-2789
Newman BW, Zhang Q, Lu Y, et al. (2011) Abstract 3350: Inhibition of breast cancer and cancer stem cells via a novel micheliolide analogue CY-9 Cancer Research. 71: 3350-3350
Zhang T, Li Y, Zhu Z, et al. (2010) MEK inhibition potentiates the activity of Hsp90 inhibitor 17-AAG against pancreatic cancer cells. Molecular Pharmaceutics. 7: 1576-84
Li Y, Zhang T, Korkaya H, et al. (2010) Sulforaphane, a dietary component of broccoli/broccoli sprouts, inhibits breast cancer stem cells. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 16: 2580-90
Yu Y, Hamza A, Zhang T, et al. (2010) Withaferin A targets heat shock protein 90 in pancreatic cancer cells. Biochemical Pharmacology. 79: 542-51
Li Y, Zhang T, Korkaya H, et al. (2010) Abstract 4271: Sulforaphane, a Dietary Component of Broccoli/Broccoli Sprouts, Inhibits Breast Cancer Stem Cells Cancer Research. 70: 4271-4271
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