Eric A. Ortlund, Ph.D.
Affiliations: | 2002 | University of South Carolina, Columbia, SC |
Area:
Organic Chemistry, BiochemistryGoogle:
"Eric Ortlund"Mean distance: (not calculated yet)
Parents
Sign in to add mentor| Lukasz Lebioda | grad student | 2002 | University of South Carolina | |
| (Crystallographic and biochemical studies of Pseudomonas 7A glutaminase-asparaginase, human prostatic acid phosphatase, human complement C8gamma and chicken annexin V.) | ||||
| Matthew R. Redinbo | post-doc | UNC Chapel Hill | ||
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Publications
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| Proffitt MR, Liu X, Ortlund EA, et al. (2023) Evolution of androgen receptors contributes to species variation in androgenic regulation of communication signals in electric fishes. Molecular and Cellular Endocrinology. 112068 |
| Mays SG, Hercules D, Ortlund EA, et al. (2023) The nuclear receptor LRH-1 discriminates between ligands using distinct allosteric signaling circuits. Protein Science : a Publication of the Protein Society. e4754 |
| Cato ML, D'Agostino EH, Spurlin RM, et al. (2023) Comparison of Activity, Structure, and Dynamics of SF-1 and LRH-1 Complexed with Small Molecule Modulators. The Journal of Biological Chemistry. 104921 |
| Mays SG, Hercules D, Ortlund EA, et al. (2023) The nuclear receptor LRH-1 discriminates between ligands using distinct allosteric signaling circuits. Biorxiv : the Preprint Server For Biology |
| Cato ML, Cornelison JL, Spurlin RM, et al. (2022) Differential Modulation of Nuclear Receptor LRH-1 through Targeting Buried and Surface Regions of the Binding Pocket. Journal of Medicinal Chemistry |
| Mays SG, D'Agostino EH, Flynn AR, et al. (2022) A phospholipid mimetic targeting LRH-1 ameliorates colitis. Cell Chemical Biology |
| Frank F, Ortlund EA, Liu X. (2021) Structural insights into glucocorticoid receptor function. Biochemical Society Transactions |
| Frank F, Liu X, Ortlund EA. (2021) Glucocorticoid receptor condensates link DNA-dependent receptor dimerization and transcriptional transactivation. Proceedings of the National Academy of Sciences of the United States of America. 118 |
| Bruno NE, Nwachukwu JC, Srinivasan S, et al. (2021) Chemical systems biology reveals mechanisms of glucocorticoid receptor signaling. Nature Chemical Biology |
| Mays SG, Stec J, Liu X, et al. (2020) Enantiomer-specific activities of an LRH-1 and SF-1 dual agonist. Scientific Reports. 10: 22279 |