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Lilu Guo, Ph.D.

Affiliations: 
2008 Chemistry University of Montana, Missoula, MT 
Area:
Organic Chemistry
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Charles M. Thompson grad student 2008 Univ. Montana
 (Exploring the interaction between asymmetric phosphonates and acetylcholinesterase. Probing the gorge and P-site via customized covalent modification.)

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Guo L, Suarez AI, Braden MR, et al. (2010) Inhibition of acetylcholinesterase by chromophore-linked fluorophosphonates. Bioorganic & Medicinal Chemistry Letters. 20: 1194-7
Bharate SB, Guo L, Reeves TE, et al. (2010) Bisquaternary pyridinium oximes: Comparison of in vitro reactivation potency of compounds bearing aliphatic linkers and heteroaromatic linkers for paraoxon-inhibited electric eel and recombinant human acetylcholinesterase. Bioorganic & Medicinal Chemistry. 18: 787-94
Guo L, Suarez AI, Thompson CM. (2010) Inactivation of acetylcholinesterase by various fluorophores. Journal of Enzyme Inhibition and Medicinal Chemistry. 25: 116-20
Bharate SB, Guo L, Reeves TE, et al. (2009) New series of monoquaternary pyridinium oximes: Synthesis and reactivation potency for paraoxon-inhibited electric eel and recombinant human acetylcholinesterase. Bioorganic & Medicinal Chemistry Letters. 19: 5101-4
Guo L, Thompson CM, Twamley B. (2009) Diastereomers (R(C),S(P))- and (R(C),R(P))-S-methyl P-(3-azidopropyl)-N-[(1R)-1-phenylethyl]phosphonamidothioate. Acta Crystallographica. Section C, Crystal Structure Communications. 65: o179-82
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