Matthew A. Cerny, Ph.D.
Affiliations: | 2005 | University of Kansas, Lawrence, KS, United States |
Area:
Pharmaceutical ChemistryGoogle:
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Parents
Sign in to add mentor| Robert Paul Hanzlik | grad student | 2005 | University of Kansas | |
| (Microsomal metabolism of N-benzyl-N-cyclopropylamine: Role of N-oxidation in the inactivation of cytochromes P450.) | ||||
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| Ramsden D, Smith D, Arenas R, et al. (2018) Identification and characterization of a selective human carbonyl reductase 1 substrate. Drug Metabolism and Disposition: the Biological Fate of Chemicals |
| Sadeque AJ, Usmani KA, Palamar S, et al. (2012) Identification of human UDP-glucuronosyltransferases involved in N-carbamoyl glucuronidation of lorcaserin. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 40: 772-8 |
| Yano JK, Denton TT, Cerny MA, et al. (2006) Synthetic inhibitors of cytochrome P-450 2A6: inhibitory activity, difference spectra, mechanism of inhibition, and protein cocrystallization. Journal of Medicinal Chemistry. 49: 6987-7001 |
| Cerny MA, Hanzlik RP. (2006) Cytochrome P450-catalyzed oxidation of N-benzyl-N-cyclopropylamine generates both cyclopropanone hydrate and 3-hydroxypropionaldehyde via hydrogen abstraction, not single electron transfer. Journal of the American Chemical Society. 128: 3346-54 |
| Cerny MA, Hanzlik RP. (2005) Cyclopropylamine inactivation of cytochromes P450: role of metabolic intermediate complexes. Archives of Biochemistry and Biophysics. 436: 265-75 |
| Lucas LH, Cerny MA, Koen YM, et al. (2004) 1H high-resolution magic-angle spinning (HR-MAS) NMR analysis of ligand density on resins using a resin internal standard. Analytical and Bioanalytical Chemistry. 380: 627-31 |