Silvia R. da Costa, Ph.D.

Affiliations: 
2002 University of Southern California, Los Angeles, CA, United States 
Area:
Cell Biology, Biochemistry
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"Silvia da Costa"
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Sarah Hamm-Alvarez grad student 2002 USC
 (How cells cry: The cytoskeleton as a facilitator of regulated secretion and membrane trafficking in lacrimal gland acinar cells.)
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Publications

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Wu K, Jerdeva GV, da Costa SR, et al. (2006) Molecular mechanisms of lacrimal acinar secretory vesicle exocytosis. Experimental Eye Research. 83: 84-96
Ding C, MacVeigh M, Pidgeon M, et al. (2006) Unique ultrastructure of exorbital lacrimal glands in male NOD and BALB/c mice. Current Eye Research. 31: 13-22
da Costa SR, Wu K, Veigh MM, et al. (2006) Male NOD mouse external lacrimal glands exhibit profound changes in the exocytotic pathway early in postnatal development. Experimental Eye Research. 82: 33-45
da Costa SR, Okamoto CT, Hamm-Alvarez SF. (2003) Actin microfilaments et al.--the many components, effectors and regulators of epithelial cell endocytosis. Advanced Drug Delivery Reviews. 55: 1359-83
Da Costa SR, Sou E, Xie J, et al. (2003) Impairing actin filament or syndapin functions promotes accumulation of clathrin-coated vesicles at the apical plasma membrane of acinar epithelial cells. Molecular Biology of the Cell. 14: 4397-413
Wang Y, Jerdeva G, Yarber FA, et al. (2003) Cytoplasmic dynein participates in apically targeted stimulated secretory traffic in primary rabbit lacrimal acinar epithelial cells. Journal of Cell Science. 116: 2051-65
da Costa SR, Andersson S, Arber F, et al. (2002) Cytoskeletal participation in stimulated secretion and compensatory apical plasma membrane retrieval in lacrimal gland acinar cells. Advances in Experimental Medicine and Biology. 506: 199-205
da Costa SR, Wang Y, Vilalta PM, et al. (2000) Changes in cytoskeletal organization in polyoma middle T antigen-transformed fibroblasts: involvement of protein phosphatase 2A and src tyrosine kinases. Cell Motility and the Cytoskeleton. 47: 253-68
Zhang L, da Costa SR, Yarber FA, et al. (2000) Protein phosphatase inhibitors alter cellular microtubules and reduce carbachol-dependent protein secretion in lacrimal acini. Current Eye Research. 20: 373-83
Hamm-Alvarez SF, da Costa SR, Sonee M, et al. (1998) Kinesin activation drives the retrieval of secretory membranes following secretion in rabbit lacrimal acinar cells. Advances in Experimental Medicine and Biology. 438: 177-80
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