Alejandro Paladini

Affiliations: 
UBA, Ubá, Minas Gerais, Brazil 
Area:
Biochemistry
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"Alejandro Paladini"
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Publications

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Martínez MC, Fernandez SP, Loscalzo LM, et al. (2009) Hesperidin, a flavonoid glycoside with sedative effect, decreases brain pERK1/2 levels in mice. Pharmacology, Biochemistry, and Behavior. 92: 291-6
Marder M, Viola H, Wasowski C, et al. (2003) 6-methylapigenin and hesperidin: new valeriana flavonoids with activity on the CNS. Pharmacology, Biochemistry, and Behavior. 75: 537-45
Wasowski C, Marder M, Viola H, et al. (2002) Isolation and identification of 6-methylapigenin, a competitive ligand for the brain GABA(A) receptors, from Valeriana wallichii. Planta Medica. 68: 934-6
Marder M, Estiú G, Blanch LB, et al. (2001) Molecular modeling and QSAR analysis of the interaction of flavone derivatives with the benzodiazepine binding site of the GABA(A) receptor complex. Bioorganic & Medicinal Chemistry. 9: 323-35
Viola H, Marder M, Wasowski C, et al. (2000) 6,3'-dibromoflavone and 6-nitro-3'-bromoflavone: new additions to the 6,3'-disubstituted flavone family of high-affinity ligands of the brain benzodiazepine binding site with agonistic properties. Biochemical and Biophysical Research Communications. 273: 694-8
Viola H, Wolfman C, Marder M, et al. (2000) 6-Chloro-3'-nitroflavone is a potent ligand for the benzodiazepine binding site of the GABA(A) receptor devoid of intrinsic activity. Pharmacology, Biochemistry, and Behavior. 65: 313-20
Viola H, Marder M, Nuñez J, et al. (1999) 6-Methyl-3'-bromoflavone, a high-affinity ligand for the benzodiazepine binding site of the GABA(A) receptor with some antagonistic properties. Biochemical and Biophysical Research Communications. 262: 643-6
Paladini AC, Marder M, Viola H, et al. (1999) Flavonoids and the central nervous system: from forgotten factors to potent anxiolytic compounds. The Journal of Pharmacy and Pharmacology. 51: 519-26
Medina JH, Viola H, Wolfman C, et al. (1998) Neuroactive flavonoids: new ligands for the Benzodiazepine receptors. Phytomedicine : International Journal of Phytotherapy and Phytopharmacology. 5: 235-43
Wolfman C, Viola H, Marder M, et al. (1998) Pharmacological characterization of 6-bromo-3'-nitroflavone, a synthetic flavonoid with high affinity for the benzodiazepine receptors. Pharmacology, Biochemistry, and Behavior. 61: 239-46
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