Frances J. Sharom
Affiliations: | University of Guelph (Canada), Guelph, Ontario, Canada |
Area:
BiochemistryWebsite:
https://www.uoguelph.ca/mcb/people/dr-frances-j-sharomGoogle:
"Frances Jane Sharom" OR "Frances J. Sharom"Mean distance: (not calculated yet)
Parents
Sign in to add mentor| Chris W.M. Grant | grad student | 1978 | The University of Western Ontario (Canada) | |
| (Behaviour and interactions of membrane carbohydrate-bearing components) | ||||
Children
Sign in to add trainee| Marty T. Lehto | grad student | 2001 | University of Guelph (Canada) |
| Qin Qu | grad student | 2003 | University of Guelph (Canada) |
| Christophe Fares | grad student | 2004 | University of Guelph (Canada) |
| R. S. Houliston | grad student | 2004 | University of Guelph (Canada) |
| Galina Radeva | grad student | 2004 | University of Guelph (Canada) |
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Publications
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| Clay AT, Lu P, Sharom FJ. (2015) Interaction of the P-Glycoprotein Multidrug Transporter with Sterols. Biochemistry. 54: 6586-97 |
| Sharom FJ. (2014) Complex Interplay between the P-Glycoprotein Multidrug Efflux Pump and the Membrane: Its Role in Modulating Protein Function. Frontiers in Oncology. 4: 41 |
| Clay AT, Sharom FJ. (2013) Lipid bilayer properties control membrane partitioning, binding, and transport of p-glycoprotein substrates. Biochemistry. 52: 343-54 |
| King G, Sharom FJ. (2012) Proteins that bind and move lipids: MsbA and NPC1. Critical Reviews in Biochemistry and Molecular Biology. 47: 75-95 |
| Sharom FJ. (2011) Flipping and flopping--lipids on the move. Iubmb Life. 63: 736-46 |
| Eckford PD, Sharom FJ. (2010) The reconstituted Escherichia coli MsbA protein displays lipid flippase activity. The Biochemical Journal. 429: 195-203 |
| Sharom FJ. (2010) GPI-anchored proteins: Biophysical behaviour and cleavage by PI-specific phospholipases Gpi Membrane Anchors-the Much Needed Link: a Biological, Structural, Physical and Chemical Look At Glycosylphosphatidylinositol-Anchored Proteins and Their Influences and Potential Applications in Biotechnology and Biomedicine. 34-52 |
| Parfitt AD, Sharom FJ. (2010) Interaction of Bacterial PI-Specific Phospholipase C With Lipid Bilayer Surfaces Biophysical Journal. 98: 87a |
| Juhasz J, Sharom FJ, Davis JH. (2009) Quantitative characterization of coexisting phases in DOPC/DPPC/cholesterol mixtures: comparing confocal fluorescence microscopy and deuterium nuclear magnetic resonance. Biochimica Et Biophysica Acta. 1788: 2541-52 |
| Siarheyeva A, Sharom FJ. (2009) The ABC transporter MsbA interacts with lipid A and amphipathic drugs at different sites. The Biochemical Journal. 419: 317-28 |