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Wei-Jen Tang

Affiliations: 
University of Chicago, Chicago, IL 
Area:
Molecular Biology, Biochemistry
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"Wei-Jen Tang"
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Children

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Chester L. Drum grad student 2002 Chicago
Jeff A. Beeler grad student 2003 Chicago
Natalia L. Zhukovskaya grad student 2005 Chicago

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Publications

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Mancl JM, Suarez C, Liang WG, et al. (2020) exoenzyme Y directly bundles actin filaments. The Journal of Biological Chemistry
Leroux F, Bosc D, Beghyn T, et al. (2019) Identification of ebselen as a potent inhibitor of insulin degrading enzyme by a drug repurposing screening. European Journal of Medicinal Chemistry. 179: 557-566
Liang WG, Triandafillou CG, Huang TY, et al. (2016) Structural basis for oligomerization and glycosaminoglycan binding of CCL5 and CCL3. Proceedings of the National Academy of Sciences of the United States of America
Lübker C, Dove S, Tang WJ, et al. (2015) Different Roles of N-Terminal and C-Terminal Domains in Calmodulin for Activation of Bacillus anthracis Edema Factor. Toxins. 7: 2598-614
Liang WG, Ren M, Zhao F, et al. (2015) Structures of human CCL18, CCL3, and CCL4 reveal molecular determinants for quaternary structures and sensitivity to insulin-degrading enzyme. Journal of Molecular Biology. 427: 1345-58
King JV, Liang WG, Scherpelz KP, et al. (2014) Molecular basis of substrate recognition and degradation by human presequence protease. Structure (London, England : 1993). 22: 996-1007
Charton J, Gauriot M, Guo Q, et al. (2014) Imidazole-derived 2-[N-carbamoylmethyl-alkylamino]acetic acids, substrate-dependent modulators of insulin-degrading enzyme in amyloid-β hydrolysis. European Journal of Medicinal Chemistry. 79: 184-93
Beste KY, Spangler CM, Burhenne H, et al. (2013) Nucleotidyl cyclase activity of particulate guanylyl cyclase A: comparison with particulate guanylyl cyclases E and F, soluble guanylyl cyclase and bacterial adenylyl cyclases CyaA and edema factor. Plos One. 8: e70223
McCord LA, Liang WG, Dowdell E, et al. (2013) Conformational states and recognition of amyloidogenic peptides of human insulin-degrading enzyme. Proceedings of the National Academy of Sciences of the United States of America. 110: 13827-32
Tripathi A, Saini V, Marchese A, et al. (2013) Modulation of the CXC chemokine receptor 4 agonist activity of ubiquitin through C-terminal protein modification. Biochemistry. 52: 4184-92
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