Jonathan J. Abramson

Affiliations: 
Portland State University, Portland, OR, United States 
Area:
General Biophysics, Biochemistry
Website:
https://www.pdx.edu/physics/physics-department-faculty
Google:
"Jonathan Abramson"
Bio:

https://www.pas.rochester.edu/graduate/alumni-1970-1979.html

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Parents

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Frederick Lobkowicz grad student 1975 Rochester (Physics Tree)
 (Inelastic omega photoproduction at 9.75 GeV/c.)
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Publications

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Klipp RC, Li N, Wang Q, et al. (2017) EL20, A Potent Antiarrhythmic Compound, Selectively Inhibits Calmodulin Deficient Ryanodine Receptor Type 2. Heart Rhythm
Li N, Wang Q, Sibrian-Vazquez M, et al. (2016) Treatment of catecholaminergic polymorphic ventricular tachycardia in mice using novel RyR2-modifying drugs. International Journal of Cardiology
Klipp RC, Li N, Wang Q, et al. (2016) Novel Compounds Inhibit Calmodulin Deficient RyR2 Activity and Arrhythmias in a CPVT Mouse Model Biophysical Journal. 110: 97a
Owen LJ, Strongin RM, Singer JD, et al. (2015) Elevated Homocysteine Levels Result in Carbonyl Formation on RyR2 and Enhanced Sensitivity of Sarcoplasmic Reticulum to Activation by Calcium Biophysical Journal. 108: 263a
Kim JJ, Němec J, Papp R, et al. (2013) Bradycardia alters Ca(2+) dynamics enhancing dispersion of repolarization and arrhythmia risk. American Journal of Physiology. Heart and Circulatory Physiology. 304: H848-60
Parikh A, Mantravadi R, Kozhevnikov D, et al. (2012) Ranolazine stabilizes cardiac ryanodine receptors: a novel mechanism for the suppression of early afterdepolarization and torsades de pointes in long QT type 2. Heart Rhythm : the Official Journal of the Heart Rhythm Society. 9: 953-60
Ye Y, Yaeger D, Owen LJ, et al. (2012) Designing calcium release channel inhibitors with enhanced electron donor properties: stabilizing the closed state of ryanodine receptor type 1. Molecular Pharmacology. 81: 53-62
Ye Y, Yaeger D, Owen LJ, et al. (2011) Designing New Ca2+ Release Channel Inhibitors Based on Enhanced Electron Donor Characteristics Biophysical Journal. 100: 417a
Smejtek P, Satterfield LE, Word RC, et al. (2010) Electrophoretic mobility of sarcoplasmic reticulum vesicles is determined by amino acids of A+P+N domains of Ca2+-ATPase. Biochimica Et Biophysica Acta. 1798: 1689-97
Jurynec MJ, Xia R, Mackrill JJ, et al. (2008) Selenoprotein N is required for ryanodine receptor calcium release channel activity in human and zebrafish muscle. Proceedings of the National Academy of Sciences of the United States of America. 105: 12485-90
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