Gina T. Kirsammer, Ph.D.

Affiliations: 
2007 University of Chicago, Chicago, IL 
Area:
Molecular Biology
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"Gina Kirsammer"
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John D. Crispino grad student 2007 Chicago
 (GATA1 and trisomy 21 in the megakaryoblastic leukemia of Down syndrome.)
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Publications

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Melo-Cardenas J, Xu Y, Wei J, et al. (2018) USP22 deficiency leads to myeloid leukemia upon oncogenic Kras activation through a PU.1 dependent mechanism. Blood
Kirsammer G, Crispino JD. (2016) Signaling a link between interferon and the traits of Down syndrome. Elife. 5
Kirsammer G, Crispino JD. (2016) Signaling a link between interferon and the traits of down syndrome: Elevated interferon signaling is a hallmark of down syndrome Elife. 5
Kirsammer G, Schultz RF, Rastogi R, et al. (2016) A PDZ-Binding Motif in DCAF7 Maintains Hematopoietic Homeostasis and Prevents Malignancy in DS-AMKL Blood. 128: 1205-1205
Goldenson B, Kirsammer G, Stankiewicz MJ, et al. (2015) Aurora kinase A is required for hematopoiesis but is dispensable for murine megakaryocyte endomitosis and differentiation. Blood. 125: 2141-50
Kirsammer G, Strizzi L, Margaryan NV, et al. (2014) Nodal signaling promotes a tumorigenic phenotype in human breast cancer. Seminars in Cancer Biology. 29: 40-50
Seftor EA, Seftor RE, Weldon DS, et al. (2014) Melanoma tumor cell heterogeneity: a molecular approach to study subpopulations expressing the embryonic morphogen nodal. Seminars in Oncology. 41: 259-66
Malinge S, Bliss-Moreau M, Kirsammer G, et al. (2012) Increased dosage of the chromosome 21 ortholog Dyrk1a promotes megakaryoblastic leukemia in a murine model of Down syndrome. The Journal of Clinical Investigation. 122: 948-62
Hardy KM, Kirschmann DA, Seftor EA, et al. (2012) Abstract 5204: Mechanisms of Notch4-Nodal regulation of the aggressive melanoma phenotype Cancer Research. 72: 5204-5204
Kirsammer G, Strizzi L, Gilgur A, et al. (2012) Abstract 3353: Nodal signaling mediates the aggressive, tumorigenic phenotype in breast cancer cells Cancer Research. 72: 3353-3353
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