James M. Vergis, Ph.D.

Affiliations: 
2002 Yale University, New Haven, CT 
Area:
Biochemistry, General Biophysics
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"James Vergis"
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G Peter Beardsley grad student 2002 Yale
 (Human aminoimidazole carboxamide ribonucleotide formyltranferase/inosine monophosphate cyclohydrolase bifunctional enzyme: Oligomeric state studies and catalytic mechanism of the cyclohydrolase activity.)
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Publications

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Simon NC, Vergis JM, Ebrahimi AV, et al. (2013) Host cell cytotoxicity and cytoskeleton disruption by CerADPr, an ADP-ribosyltransferase of Bacillus cereus G9241. Biochemistry. 52: 2309-18
Vergis JM, Wiener MC. (2011) The variable detergent sensitivity of proteases that are utilized for recombinant protein affinity tag removal. Protein Expression and Purification. 78: 139-42
Vergis JM, Purdy MD, Wiener MC. (2010) A high-throughput differential filtration assay to screen and select detergents for membrane proteins. Analytical Biochemistry. 407: 1-11
Vergis JM, Beardsley GP. (2004) Catalytic mechanism of the cyclohydrolase activity of human aminoimidazole carboxamide ribonucleotide formyltransferase/inosine monophosphate cyclohydrolase. Biochemistry. 43: 1184-92
Vergis JM, Bulock KG, Fleming KG, et al. (2001) Human 5-aminoimidazole-4-carboxamide ribonucleotide transformylase/inosine 5'-monophosphate cyclohydrolase. A bifunctional protein requiring dimerization for transformylase activity but not for cyclohydrolase activity. The Journal of Biological Chemistry. 276: 7727-33
Beardsley GP, Rayl EA, Gunn K, et al. (1998) Structure and functional relationships in human pur H. Advances in Experimental Medicine and Biology. 431: 221-6
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