Michael C. Edler, Ph.D.
Affiliations: | 2003 | University of Utah, Salt Lake City, UT |
Area:
Pharmacology, ToxicologyGoogle:
"Michael Edler"Mean distance: (not calculated yet)
Parents
Sign in to add mentor| Louis R. Barrows | grad student | 2003 | University of Utah | |
| (Discovery and characterization of tubulin -interactive peptides.) | ||||
BETA: Related publications
See more...
Publications
|
You can help our author matching system! If you notice any publications incorrectly attributed to this author, please sign in and mark matches as correct or incorrect. |
| Kong Y, Edler MC, Hamel E, et al. (2024) Synthesis and structure-activity relationship of boronic acid bioisosteres of combretastatin A-4 as anticancer agents. Bioorganic & Medicinal Chemistry. 116: 117999 |
| Kong Y, Wang K, Edler MC, et al. (2010) A boronic acid chalcone analog of combretastatin A-4 as a potent anti-proliferation agent. Bioorganic & Medicinal Chemistry. 18: 971-7 |
| La Regina G, Sarkar T, Bai R, et al. (2009) New arylthioindoles and related bioisosteres at the sulfur bridging group. 4. Synthesis, tubulin polymerization, cell growth inhibition, and molecular modeling studies Journal of Medicinal Chemistry. 52: 7512-7527 |
| Edler MC, Yang G, Katherine Jung M, et al. (2009) Demonstration of microtubule-like structures formed with (-)-rhazinilam from purified tubulin outside of cells and a simple tubulin-based assay for evaluation of analog activity Archives of Biochemistry and Biophysics. 487: 98-104 |
| Shin Y, Fournier JH, Brückner A, et al. (2007) Synthesis and biological evaluation of (-)-dictyostatin and stereoisomers. Tetrahedron. 63: 8537-8562 |
| La Regina G, Edler MC, Brancale A, et al. (2007) Arylthioindole inhibitors of tubulin polymerization. 3. Biological evaluation, structure-activity relationships and molecular modeling studies. Journal of Medicinal Chemistry. 50: 2865-74 |
| Buey RM, Calvo E, Barasoain I, et al. (2007) Cyclostreptin binds covalently to microtubule pores and lumenal taxoid binding sites. Nature Chemical Biology. 3: 117-25 |
| De Martino G, Edler MC, La Regina G, et al. (2006) New arylthioindoles: potent inhibitors of tubulin polymerization. 2. Structure-activity relationships and molecular modeling studies. Journal of Medicinal Chemistry. 49: 947-54 |
| Edler MC, Buey RM, Gussio R, et al. (2006) Erratum: Cyclostreptin (FR182877), an antitumor tubulin-polymerizing agent deficient in enhancing tubulin assembly despite its high affinity for the taxoid site (Biochemistry (August 30, 2005) 44, 34 (11525-11538)) Biochemistry. 45 |
| Madiraju C, Edler MC, Hamel E, et al. (2005) Tubulin assembly, taxoid site binding, and cellular effects of the microtubule-stabilizing agent dictyostatin. Biochemistry. 44: 15053-63 |