John R. Goodell, Ph.D.

Affiliations: 
2006 University of Minnesota, Twin Cities, Minneapolis, MN 
Area:
Pharmaceutical Chemistry, Organic Chemistry, Biochemistry
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David M. Ferguson grad student 2006 UMN
 (Synthesis and evaluation of heterocyclic antiviral agents.)
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Publications

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Simanis JA, Zwick CR, Woodall EL, et al. (2015) Further investigation of pyranone activation Heterocycles. 91: 149-156
Simanis JA, Law CM, Woodall EL, et al. (2014) Investigation of oxidopyrylium-alkene [5+2] cycloaddition conjugate addition cascade (C3) sequences. Chemical Communications (Cambridge, England). 50: 9130-3
Benoit AR, Schiaffo C, Salomon CE, et al. (2014) Synthesis and evaluation of N-alkyl-9-aminoacridines with antibacterial activity. Bioorganic & Medicinal Chemistry Letters. 24: 3014-7
Woodall EL, Simanis JA, Hamaker CG, et al. (2013) Unique reactivity of anti- and syn-acetoxypyranones en route to oxidopyrylium intermediates leading to a cascade process. Organic Letters. 15: 3270-3
Brummond KM, Goodell JR, Laporte MG, et al. (2012) Synthesis and in silico screening of a library of β-carboline-containing compounds. Beilstein Journal of Organic Chemistry. 8: 1048-58
Goodell JR, Poole JL, Beeler AB, et al. (2011) Synthesis and reactivity of bicyclo[3.2.1]octanoid-derived cyclopropanes. The Journal of Organic Chemistry. 76: 9792-800
Treece JL, Goodell JR, Vander Velde D, et al. (2010) Reaction discovery using microfluidic-based multidimensional screening of polycyclic iminium ethers. The Journal of Organic Chemistry. 75: 2028-38
Giri R, Goodell JR, Xing C, et al. (2010) Synthesis and cancer cell cytotoxicity of substituted xanthenes. Bioorganic & Medicinal Chemistry. 18: 1456-63
Oppegard LM, Ougolkov AV, Luchini DN, et al. (2009) Novel acridine-based compounds that exhibit an anti-pancreatic cancer activity are catalytic inhibitors of human topoisomerase II. European Journal of Pharmacology. 602: 223-9
Goodell JR, Ougolkov AV, Hiasa H, et al. (2008) Acridine-based agents with topoisomerase II activity inhibit pancreatic cancer cell proliferation and induce apoptosis. Journal of Medicinal Chemistry. 51: 179-82
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