Lillian DeBruin, Ph.D.

Affiliations: 
2001 University of Guelph (Canada), Guelph, Ontario, Canada 
Area:
Biochemistry
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P David Josephy grad student 2001 University of Guelph (Canada)
 (The detection of aromatic amines, possible mammary carcinogens, in human milk.)
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Publications

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Josephy PD, Summerscales J, DeBruin LS, et al. (2002) N-hydroxyarylamine O-acetyltransferase-deficient Escherichia coli strains are resistant to the mutagenicity of nitro compounds. Biological Chemistry. 383: 977-82
DeBruin LS, Josephy PD. (2002) Perspectives on the chemical etiology of breast cancer. Environmental Health Perspectives. 110: 119-28
DeBruin LS, Martos PA, Josephy PD. (2001) Detection of PhIP (2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine) in the milk of healthy women. Chemical Research in Toxicology. 14: 1523-8
DeBruin LS, Pawliszyn JB, Josephy PD. (1999) Detection of monocyclic aromatic amines, possible mammary carcinogens, in human milk. Chemical Research in Toxicology. 12: 78-82
DeBruin LS, Josephy PD, Pawliszyn JB. (1998) Solid-phase microextraction of monocyclic aromatic amines from biological fluids. Analytical Chemistry. 70: 1986-92
Josephy PD, DeBruin LS, Lord HL, et al. (1995) Bioactivation of aromatic amines by recombinant human cytochrome P4501A2 expressed in Ames tester strain bacteria: a substitute for activation by mammalian tissue preparations. Cancer Research. 55: 799-802
Smith BJ, DeBruin L, Josephy PD, et al. (1992) Mutagenic activation of benzidine requires prior bacterial acetylation and subsequent conversion by prostaglandin H synthase to 4-nitro-4'-(acetylamino)biphenyl. Chemical Research in Toxicology. 5: 431-9
Smith BJ, DeBruin L, Josephy PD, et al. (1992) Mutagenic activation of benzidine requires prior bacterial acetylation and subsequent conversion by prostaglandin H synthase to 4-nitro-4′-(acetylamino)biphenyl Chemical Research in Toxicology. 5: 431-439
DeBruin LS, Josephy PD. (1989) Dichlorobenzidine-DNA binding catalyzed by peroxidative activation in Salmonella typhimurium. Archives of Biochemistry and Biophysics. 269: 25-31
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