Juan A. Faraldos, Ph.D.

Affiliations: 
2003 SUNY College of Environmental Science and Forestry, Syracuse, NY, United States 
Area:
Organic Chemistry, Biochemistry
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"Juan Faraldos"
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Parents

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Jose-Luis Giner grad student 2003 SUNY ESF
 (Biomimetic studies on steroidal orthoesters.)
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Publications

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Demiray M, Tang X, Wirth T, et al. (2017) An Efficient Chemoenzymatic Synthesis of Dihydroartemisinic Aldehyde. Angewandte Chemie (International Ed. in English)
Faraldos JA, Grundy DJ, Cascon O, et al. (2016) Enzymatic synthesis of natural (+)-aristolochene from a non-natural substrate. Chemical Communications (Cambridge, England)
Chen M, Chou WK, Al-Lami N, et al. (2016) Probing the Role of Active Site Water in the Sesquiterpene Cyclization Reaction Catalyzed by Aristolochene Synthase. Biochemistry
Salmon M, Laurendon C, Vardakou M, et al. (2015) Emergence of terpene cyclization in Artemisia annua. Nature Communications. 6: 6143
Vardakou M, Salmon M, Faraldos JA, et al. (2014) Comparative analysis and validation of the malachite green assay for the high throughput biochemical characterization of terpene synthases. Methodsx. 1: 187-96
Gonzalez V, Touchet S, Grundy DJ, et al. (2014) Evolutionary and mechanistic insights from the reconstruction of α-humulene synthases from a modern (+)-germacrene A synthase. Journal of the American Chemical Society. 136: 14505-12
Faraldos JA, Coates RM, Giner JL. (2013) Alternative synthesis of the Colorado potato beetle pheromone. The Journal of Organic Chemistry. 78: 10548-54
Chen M, Al-lami N, Janvier M, et al. (2013) Mechanistic insights from the binding of substrate and carbocation intermediate analogues to aristolochene synthase. Biochemistry. 52: 5441-53
Li JX, Fang X, Zhao Q, et al. (2013) Rational engineering of plasticity residues of sesquiterpene synthases from Artemisia annua: product specificity and catalytic efficiency. The Biochemical Journal. 451: 417-26
Faraldos JA, Gonzalez V, Li A, et al. (2012) Probing the mechanism of 1,4-conjugate elimination reactions catalyzed by terpene synthases. Journal of the American Chemical Society. 134: 20844-8
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