Bradley E. Poulsen, Ph.D.

Affiliations: 
2012 Biochemistry University of Toronto, Toronto, ON, Canada 
Area:
Biochemistry
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"Bradley Poulsen"
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Parents

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Deborah T. Hung grad student 2012- Harvard (Microtree)
Charles Deber grad student 2012 University of Toronto
 (Characterization and inhibition of the dimer interface in bacterial small multidrug resistance proteins.)
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Publications

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Poulsen BE, Warrier T, Barkho S, et al. (2024) "Multiplexed screen identifies a -specific small molecule targeting the outer membrane protein OprH and its interaction with LPS". Biorxiv : the Preprint Server For Biology
Poulsen BE, Clatworthy AE, Hung DT. (2022) The Use of Tn-Seq and the FiTnEss Analysis to Define the Core Essential Genome of Pseudomonas aeruginosa. Methods in Molecular Biology (Clifton, N.J.). 2377: 179-197
Romano KP, Warrier T, Poulsen BE, et al. (2019) Mutations in confer cross-resistance between the LptD inhibitor POL7080 and colistin in . Antimicrobial Agents and Chemotherapy
Poulsen BE, Yang R, Clatworthy AE, et al. (2019) Defining the core essential genome of . Proceedings of the National Academy of Sciences of the United States of America
Bellmann-Sickert K, Stone TA, Poulsen BE, et al. (2015) Efflux by small multidrug resistance proteins is inhibited by membrane-interactive helix-stapled peptides. The Journal of Biological Chemistry. 290: 1752-9
Poulsen BE, Deber CM. (2012) Drug efflux by a small multidrug resistance protein is inhibited by a transmembrane peptide. Antimicrobial Agents and Chemotherapy. 56: 3911-6
Ng DP, Poulsen BE, Deber CM. (2012) Membrane protein misassembly in disease. Biochimica Et Biophysica Acta. 1818: 1115-22
Poulsen BE, Cunningham F, Lee KK, et al. (2011) Modulation of substrate efflux in bacterial small multidrug resistance proteins by mutations at the dimer interface. Journal of Bacteriology. 193: 5929-35
Cunningham F, Poulsen BE, Ip W, et al. (2011) Beta-branched residues adjacent to GG4 motifs promote the efficient association of glycophorin A transmembrane helices. Biopolymers. 96: 340-7
Rath A, Nadeau VG, Poulsen BE, et al. (2010) Novel hydrophobic standards for membrane protein molecular weight determinations via sodium dodecyl sulfate-polyacrylamide gel electrophoresis. Biochemistry. 49: 10589-91
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