Brett S. Chevalier, Ph.D.
Affiliations: | 2002 | University of Washington, Seattle, Seattle, WA |
Area:
Molecular Biology, General BiophysicsGoogle:
"Brett Chevalier"Mean distance: (not calculated yet)
Parents
Sign in to add mentorBarry L. Stoddard | grad student | 2002 | University of Washington | |
(Homing endonuclease mechanism, structure and design.) |
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Publications
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Spiegel PC, Chevalier B, Sussman D, et al. (2006) The structure of I-CeuI homing endonuclease: Evolving asymmetric DNA recognition from a symmetric protein scaffold. Structure (London, England : 1993). 14: 869-80 |
Chevalier B, Sussman D, Otis C, et al. (2004) Metal-dependent DNA cleavage mechanism of the I-CreI LAGLIDADG homing endonuclease. Biochemistry. 43: 14015-26 |
Chevalier B, Turmel M, Lemieux C, et al. (2003) Flexible DNA target site recognition by divergent homing endonuclease isoschizomers I-CreI and I-MsoI. Journal of Molecular Biology. 329: 253-69 |
Chevalier BS, Kortemme T, Chadsey MS, et al. (2002) Design, activity, and structure of a highly specific artificial endonuclease. Molecular Cell. 10: 895-905 |
Seligman LM, Chisholm KM, Chevalier BS, et al. (2002) Mutations altering the cleavage specificity of a homing endonuclease. Nucleic Acids Research. 30: 3870-9 |
Chevalier BS, Stoddard BL. (2001) Homing endonucleases: structural and functional insight into the catalysts of intron/intein mobility. Nucleic Acids Research. 29: 3757-74 |
Chevalier BS, Monnat RJ, Stoddard BL. (2001) The homing endonuclease I-CreI uses three metals, one of which is shared between the two active sites. Nature Structural Biology. 8: 312-6 |
Galburt EA, Chadsey MS, Jurica MS, et al. (2000) Conformational changes and cleavage by the homing endonuclease I-PpoI: a critical role for a leucine residue in the active site. Journal of Molecular Biology. 300: 877-87 |
Galburt EA, Chevalier B, Tang W, et al. (1999) A novel endonuclease mechanism directly visualized for I-PpoI. Nature Structural Biology. 6: 1096-9 |